The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya.
<h4>Background</h4>Cervical cancer (CC) is preventable, yet remains a significant public health threat, particularly in Sub-Saharan Africa. Despite considerable awareness, screening rates for CC in Kenya are low and loss to follow-up following treatment for premalignant cervical lesions...
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| Format: | Article |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0318941 |
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| author | May Maloba Sarah Finocchario-Kessler Catherine Wexler Vincent Staggs Nicodemus Maosa Shadrack Babu Kathy Goggin David Hutton Gregory Ganda Hilary Mabeya Elise Robertson Natabhona Mabachi |
| author_facet | May Maloba Sarah Finocchario-Kessler Catherine Wexler Vincent Staggs Nicodemus Maosa Shadrack Babu Kathy Goggin David Hutton Gregory Ganda Hilary Mabeya Elise Robertson Natabhona Mabachi |
| author_sort | May Maloba |
| collection | DOAJ |
| description | <h4>Background</h4>Cervical cancer (CC) is preventable, yet remains a significant public health threat, particularly in Sub-Saharan Africa. Despite considerable awareness, screening rates for CC in Kenya are low and loss to follow-up following treatment for premalignant cervical lesions remains high. This study investigates the efficacy of the Cancer Tracking System (CATSystem), a web-based intervention, to improve CC screening and treatment retention.<h4>Methods</h4>A matched, cluster randomized controlled trial will be conducted in Kenyan government hospitals (n = 10) with five intervention and five standard-of-care (SOC) sites. The primary outcome is the proportion of women with a positive screen who receive appropriate treatment (onsite or referral). Secondary outcomes include CC screening uptake among all women and timeliness of treatment initiation. We will utilize mixed methods to assess intervention feasibility, acceptability, and cost-effectiveness.<h4>Discussion</h4>The CATSystem has the potential to improve CC care in Kenya by leveraging existing technology to address known barriers in the screening and treatment cascade. This study will provide valuable evidence for potential scale-up of the intervention. |
| format | Article |
| id | doaj-art-a637a784a5b34020a56ca4e68d215205 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-a637a784a5b34020a56ca4e68d2152052025-08-20T03:28:50ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01202e031894110.1371/journal.pone.0318941The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya.May MalobaSarah Finocchario-KesslerCatherine WexlerVincent StaggsNicodemus MaosaShadrack BabuKathy GogginDavid HuttonGregory GandaHilary MabeyaElise RobertsonNatabhona Mabachi<h4>Background</h4>Cervical cancer (CC) is preventable, yet remains a significant public health threat, particularly in Sub-Saharan Africa. Despite considerable awareness, screening rates for CC in Kenya are low and loss to follow-up following treatment for premalignant cervical lesions remains high. This study investigates the efficacy of the Cancer Tracking System (CATSystem), a web-based intervention, to improve CC screening and treatment retention.<h4>Methods</h4>A matched, cluster randomized controlled trial will be conducted in Kenyan government hospitals (n = 10) with five intervention and five standard-of-care (SOC) sites. The primary outcome is the proportion of women with a positive screen who receive appropriate treatment (onsite or referral). Secondary outcomes include CC screening uptake among all women and timeliness of treatment initiation. We will utilize mixed methods to assess intervention feasibility, acceptability, and cost-effectiveness.<h4>Discussion</h4>The CATSystem has the potential to improve CC care in Kenya by leveraging existing technology to address known barriers in the screening and treatment cascade. This study will provide valuable evidence for potential scale-up of the intervention.https://doi.org/10.1371/journal.pone.0318941 |
| spellingShingle | May Maloba Sarah Finocchario-Kessler Catherine Wexler Vincent Staggs Nicodemus Maosa Shadrack Babu Kathy Goggin David Hutton Gregory Ganda Hilary Mabeya Elise Robertson Natabhona Mabachi The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya. PLoS ONE |
| title | The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya. |
| title_full | The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya. |
| title_fullStr | The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya. |
| title_full_unstemmed | The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya. |
| title_short | The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya. |
| title_sort | cancer tracking system catsystem study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening treatment referral and follow up in kenya |
| url | https://doi.org/10.1371/journal.pone.0318941 |
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