Alternanthera mosaic potexvirus: Several Features, Properties, and Application
Alternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stab...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Advances in Virology |
| Online Access: | http://dx.doi.org/10.1155/2018/1973705 |
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| _version_ | 1832554970857078784 |
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| author | Ekaterina Donchenko Ekaterina Trifonova Nikolai Nikitin Joseph Atabekov Olga Karpova |
| author_facet | Ekaterina Donchenko Ekaterina Trifonova Nikolai Nikitin Joseph Atabekov Olga Karpova |
| author_sort | Ekaterina Donchenko |
| collection | DOAJ |
| description | Alternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stable in a wide range of conditions, including sera of laboratory animals. AltMV VLPs can assemble at various pH and ionic strengths. Furthermore, AltMV virions and VLPs demonstrate high immunogenicity, enhancing the immune response to the target antigen thus offering the possibility of being used as potential adjuvants. Recently, for the first time for plant viruses, we showed the structural difference between morphologically similar viral and virus-like particles on AltMV virions and VLPs. In this review, we discuss the features of AltMV virions, AltMV VLP assembly, and their structure and properties, as well as the characteristics of AltMV isolates, host plants, infection symptoms, AltMV isolation and purification, genome structure, viral proteins, and AltMV-based vectors. |
| format | Article |
| id | doaj-art-a6361b5c53f44b9fb3f8edc0dc737d7b |
| institution | Kabale University |
| issn | 1687-8639 1687-8647 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Virology |
| spelling | doaj-art-a6361b5c53f44b9fb3f8edc0dc737d7b2025-02-03T05:49:55ZengWileyAdvances in Virology1687-86391687-86472018-01-01201810.1155/2018/19737051973705Alternanthera mosaic potexvirus: Several Features, Properties, and ApplicationEkaterina Donchenko0Ekaterina Trifonova1Nikolai Nikitin2Joseph Atabekov3Olga Karpova4Department of Virology, Lomonosov Moscow State University, Moscow 119234, RussiaDepartment of Virology, Lomonosov Moscow State University, Moscow 119234, RussiaDepartment of Virology, Lomonosov Moscow State University, Moscow 119234, RussiaDepartment of Virology, Lomonosov Moscow State University, Moscow 119234, RussiaDepartment of Virology, Lomonosov Moscow State University, Moscow 119234, RussiaAlternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stable in a wide range of conditions, including sera of laboratory animals. AltMV VLPs can assemble at various pH and ionic strengths. Furthermore, AltMV virions and VLPs demonstrate high immunogenicity, enhancing the immune response to the target antigen thus offering the possibility of being used as potential adjuvants. Recently, for the first time for plant viruses, we showed the structural difference between morphologically similar viral and virus-like particles on AltMV virions and VLPs. In this review, we discuss the features of AltMV virions, AltMV VLP assembly, and their structure and properties, as well as the characteristics of AltMV isolates, host plants, infection symptoms, AltMV isolation and purification, genome structure, viral proteins, and AltMV-based vectors.http://dx.doi.org/10.1155/2018/1973705 |
| spellingShingle | Ekaterina Donchenko Ekaterina Trifonova Nikolai Nikitin Joseph Atabekov Olga Karpova Alternanthera mosaic potexvirus: Several Features, Properties, and Application Advances in Virology |
| title | Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
| title_full | Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
| title_fullStr | Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
| title_full_unstemmed | Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
| title_short | Alternanthera mosaic potexvirus: Several Features, Properties, and Application |
| title_sort | alternanthera mosaic potexvirus several features properties and application |
| url | http://dx.doi.org/10.1155/2018/1973705 |
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