Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus

Objective. To investigate the frequency of neonatal near miss (NNM) and associate it with maternal morbidity in newborns of women with type 1 diabetes mellitus (T1DM). Methods. This was a cross-sectional retrospective study from a secondary analysis of data retrieved from medical records of pregnant...

Full description

Saved in:
Bibliographic Details
Main Authors: Luiza R. Morais, Beatriz C. Patz, Felipe F. Campanharo, Patricia M. Dualib, Sue Y. Sun, Rosiane Mattar
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2019/8594158
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850169214691704832
author Luiza R. Morais
Beatriz C. Patz
Felipe F. Campanharo
Patricia M. Dualib
Sue Y. Sun
Rosiane Mattar
author_facet Luiza R. Morais
Beatriz C. Patz
Felipe F. Campanharo
Patricia M. Dualib
Sue Y. Sun
Rosiane Mattar
author_sort Luiza R. Morais
collection DOAJ
description Objective. To investigate the frequency of neonatal near miss (NNM) and associate it with maternal morbidity in newborns of women with type 1 diabetes mellitus (T1DM). Methods. This was a cross-sectional retrospective study from a secondary analysis of data retrieved from medical records of pregnant women with T1DM cared at a Brazilian university hospital between 2005 and 2015. Maternal near miss (MNM) and potentially life-threatening conditions (PTLC) were classified according to the World Health Organization criteria. NNM was classified according to the Pan American Health Organization Neonatal Near Miss Working Group criteria. Association of maternal morbidity with NNM was assessed using chi-square test. Results. There were 122 newborns (NB) among 137 T1DM pregnancies. Thirty-seven NB presented NNM—incidence of 303 NNM per 1000 live births (37/122). NNM was associated with MNM (P<0.001, OR (95% CI): 17.15 (1.85–159.12)). PLTC did not increase the odds of NNM (P=0.07; OR (95% CI): 2.1281 (0.92–4.91)). Seven newborns died, six of them from pregnancies without severe maternal morbidity. 71% of the neonatal death (5/7) occurred in malformed neonates. Conclusion. MNM was associated with NNM among women with T1DM, and PLTC, paradoxically, did not increase NNM.
format Article
id doaj-art-a62ddef2e5a24a5a8908d9df0bfaa53c
institution OA Journals
issn 1687-9589
1687-9597
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Obstetrics and Gynecology International
spelling doaj-art-a62ddef2e5a24a5a8908d9df0bfaa53c2025-08-20T02:20:47ZengWileyObstetrics and Gynecology International1687-95891687-95972019-01-01201910.1155/2019/85941588594158Neonatal Near Miss among Newborns of Women with Type 1 Diabetes MellitusLuiza R. Morais0Beatriz C. Patz1Felipe F. Campanharo2Patricia M. Dualib3Sue Y. Sun4Rosiane Mattar5Obstetrics Department, Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina, São Paulo 04021-001, BrazilObstetrics Department, Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina, São Paulo 04021-001, BrazilObstetrics Department, Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina, São Paulo 04021-001, BrazilEndocrinology Department, Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina, São Paulo 04021-001, BrazilObstetrics Department, Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina, São Paulo 04021-001, BrazilObstetrics Department, Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina, São Paulo 04021-001, BrazilObjective. To investigate the frequency of neonatal near miss (NNM) and associate it with maternal morbidity in newborns of women with type 1 diabetes mellitus (T1DM). Methods. This was a cross-sectional retrospective study from a secondary analysis of data retrieved from medical records of pregnant women with T1DM cared at a Brazilian university hospital between 2005 and 2015. Maternal near miss (MNM) and potentially life-threatening conditions (PTLC) were classified according to the World Health Organization criteria. NNM was classified according to the Pan American Health Organization Neonatal Near Miss Working Group criteria. Association of maternal morbidity with NNM was assessed using chi-square test. Results. There were 122 newborns (NB) among 137 T1DM pregnancies. Thirty-seven NB presented NNM—incidence of 303 NNM per 1000 live births (37/122). NNM was associated with MNM (P<0.001, OR (95% CI): 17.15 (1.85–159.12)). PLTC did not increase the odds of NNM (P=0.07; OR (95% CI): 2.1281 (0.92–4.91)). Seven newborns died, six of them from pregnancies without severe maternal morbidity. 71% of the neonatal death (5/7) occurred in malformed neonates. Conclusion. MNM was associated with NNM among women with T1DM, and PLTC, paradoxically, did not increase NNM.http://dx.doi.org/10.1155/2019/8594158
spellingShingle Luiza R. Morais
Beatriz C. Patz
Felipe F. Campanharo
Patricia M. Dualib
Sue Y. Sun
Rosiane Mattar
Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus
Obstetrics and Gynecology International
title Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus
title_full Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus
title_fullStr Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus
title_full_unstemmed Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus
title_short Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus
title_sort neonatal near miss among newborns of women with type 1 diabetes mellitus
url http://dx.doi.org/10.1155/2019/8594158
work_keys_str_mv AT luizarmorais neonatalnearmissamongnewbornsofwomenwithtype1diabetesmellitus
AT beatrizcpatz neonatalnearmissamongnewbornsofwomenwithtype1diabetesmellitus
AT felipefcampanharo neonatalnearmissamongnewbornsofwomenwithtype1diabetesmellitus
AT patriciamdualib neonatalnearmissamongnewbornsofwomenwithtype1diabetesmellitus
AT sueysun neonatalnearmissamongnewbornsofwomenwithtype1diabetesmellitus
AT rosianemattar neonatalnearmissamongnewbornsofwomenwithtype1diabetesmellitus