Electrochemically induced Meerwein arylation as a green strategy for the synthesis of arylbenzoquinone derivatives under batch and flow conditions
Abstract An electrochemical Meerwein arylation reaction was reported for the synthesis of aryl-benzoquinone derivatives. In this work, efficient electrochemical synthesis of aryl-benzoquinone derivatives by direct electrolysis of aqueous solution containing hydroquinone and aryldiazonium salts in ba...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-02504-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Abstract An electrochemical Meerwein arylation reaction was reported for the synthesis of aryl-benzoquinone derivatives. In this work, efficient electrochemical synthesis of aryl-benzoquinone derivatives by direct electrolysis of aqueous solution containing hydroquinone and aryldiazonium salts in batch and a homemade continuous-flow cells is reported. In the batch system, the products were obtained in a simple undivided cell equipped with a copper anode and a stainless steel cathode. In the continuous flow system, the products were obtained simply by passing hydroquinone and the aryldiazonium salt through a tube made of copper with a stainless steel rod in the center. All equipment required in both cell types is obtained from common commercial sources. This protocol is green and cost-effective due to the use of electricity and is performed under mild and safe conditions without the use of toxic solvents and catalysts. |
|---|---|
| ISSN: | 2045-2322 |