Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
Aim: to evaluate, using the “GastroPanel®”, the frequency of detection of H. pylori infection and associated gastric diseases among doctors and medical staff of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow.Materials and methods. Employ...
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Gastro LLC
2024-05-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/922 |
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| author | A. D. Kaprin N. S. Sergeeva S. S. Pirogov I. I. Alentov O. К. Yutsevich V. I. Ryabtseva G. F. Minibaeva N. V. Marshutina T. А. Karmakova |
| author_facet | A. D. Kaprin N. S. Sergeeva S. S. Pirogov I. I. Alentov O. К. Yutsevich V. I. Ryabtseva G. F. Minibaeva N. V. Marshutina T. А. Karmakova |
| author_sort | A. D. Kaprin |
| collection | DOAJ |
| description | Aim: to evaluate, using the “GastroPanel®”, the frequency of detection of H. pylori infection and associated gastric diseases among doctors and medical staff of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow.Materials and methods. Employees of three branches of the National Medical Research Radiological Centre (n = 434, mean age — 48.5 ± 0.6 years) were examined using laboratory tests “GastroPanel®” (Biohit Oyj, Finland). The test results make it possible to identify infection of the stomach with H. pylori, hypo- and hyperacid conditions, as well as atrophic gastritis of the antrum and body of the stomach, as its precancerous conditions. Esophagogastroduodenoscopy (EGDS) for suspected atrophic gastritis was performed with an Olympus GIF-HQ190 video endoscope (Japan) in a narrow-spectrum mode with close focus (NBI Dual Focus).Results. The absence of pathological signs detected by “GastroPanel®” was established in 23.3 % of cases, hyperacid state — in 18.4 %, and hypoacid state — in 5.2 %. These disorders are classified as functional. Consequently, the conditional norm in total was identified in 46.9 % of observations. An increased level of antibodies to H. pylori was found in 43.3 % of those examined. Atrophic gastritis in the body of the stomach according to the results of the “GastroPanel®” was detected in 4.8 % of cases (median age — 59 years), in the antrum (or increased secretion of hydrochloric acid) — also in 4.8 % of cases (median age — 52 years). Within two months after laboratory diagnostics, EGDS was performed for 10 out of 15 patients examined at the P. Hertsen Moscow Oncology Research Institute in whom, based on the results of the “GastroPanel®”, the presence of atrophic gastritis in the antrum (or increased secretion of hydrochloric acid) was suspected. In 6 out of 10 cases, atrophic gastritis of the antrum was confirmed (in two of them, the atrophy extended to the body of the stomach and was assessed as severe). Of the 11 people with the “GastroPanel®” conclusion “Atrophic gastritis of the body of the stomach,” an endoscopic examination was carried out in 7 persons, and in all these cases the diagnosis was confirmed, and in two people the conclusion was made of severe atrophic pangastritis.Conclusion. “GastroPanel®” confirmed its high significance in identifying H. pylori infection and precancerous atrophic changes in the gastric mucosa. Regarding the occupational risks of infection among medical workers, we consider it advisable to conduct such screening without selecting an asymptomatic population. |
| format | Article |
| id | doaj-art-a627ddae7b8745c7be714a3a5b65a07c |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2024-05-01 |
| publisher | Gastro LLC |
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| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-a627ddae7b8745c7be714a3a5b65a07c2025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732024-05-01342577110.22416/1382-4376-2024-34-2-57-71759Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationA. D. Kaprin0N. S. Sergeeva1S. S. Pirogov2I. I. Alentov3O. К. Yutsevich4V. I. Ryabtseva5G. F. Minibaeva6N. V. Marshutina7T. А. Karmakova8National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; P. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; Peoples’ Friendship University of Russia named after Patrice LumumbaP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationP. Hertsen Moscow Oncology Research Institute — the Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationAim: to evaluate, using the “GastroPanel®”, the frequency of detection of H. pylori infection and associated gastric diseases among doctors and medical staff of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, Moscow.Materials and methods. Employees of three branches of the National Medical Research Radiological Centre (n = 434, mean age — 48.5 ± 0.6 years) were examined using laboratory tests “GastroPanel®” (Biohit Oyj, Finland). The test results make it possible to identify infection of the stomach with H. pylori, hypo- and hyperacid conditions, as well as atrophic gastritis of the antrum and body of the stomach, as its precancerous conditions. Esophagogastroduodenoscopy (EGDS) for suspected atrophic gastritis was performed with an Olympus GIF-HQ190 video endoscope (Japan) in a narrow-spectrum mode with close focus (NBI Dual Focus).Results. The absence of pathological signs detected by “GastroPanel®” was established in 23.3 % of cases, hyperacid state — in 18.4 %, and hypoacid state — in 5.2 %. These disorders are classified as functional. Consequently, the conditional norm in total was identified in 46.9 % of observations. An increased level of antibodies to H. pylori was found in 43.3 % of those examined. Atrophic gastritis in the body of the stomach according to the results of the “GastroPanel®” was detected in 4.8 % of cases (median age — 59 years), in the antrum (or increased secretion of hydrochloric acid) — also in 4.8 % of cases (median age — 52 years). Within two months after laboratory diagnostics, EGDS was performed for 10 out of 15 patients examined at the P. Hertsen Moscow Oncology Research Institute in whom, based on the results of the “GastroPanel®”, the presence of atrophic gastritis in the antrum (or increased secretion of hydrochloric acid) was suspected. In 6 out of 10 cases, atrophic gastritis of the antrum was confirmed (in two of them, the atrophy extended to the body of the stomach and was assessed as severe). Of the 11 people with the “GastroPanel®” conclusion “Atrophic gastritis of the body of the stomach,” an endoscopic examination was carried out in 7 persons, and in all these cases the diagnosis was confirmed, and in two people the conclusion was made of severe atrophic pangastritis.Conclusion. “GastroPanel®” confirmed its high significance in identifying H. pylori infection and precancerous atrophic changes in the gastric mucosa. Regarding the occupational risks of infection among medical workers, we consider it advisable to conduct such screening without selecting an asymptomatic population.https://www.gastro-j.ru/jour/article/view/922gastropanelmedical workershelicobacter pyloriatrophic gastritisesophagogastroduodenoscopy |
| spellingShingle | A. D. Kaprin N. S. Sergeeva S. S. Pirogov I. I. Alentov O. К. Yutsevich V. I. Ryabtseva G. F. Minibaeva N. V. Marshutina T. А. Karmakova Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation Российский журнал гастроэнтерологии, гепатологии, колопроктологии gastropanel medical workers helicobacter pylori atrophic gastritis esophagogastroduodenoscopy |
| title | Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation |
| title_full | Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation |
| title_fullStr | Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation |
| title_full_unstemmed | Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation |
| title_short | Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation |
| title_sort | detection rate of helicobacter pylori infection and atrophic gastritis using serological markers gastropanel r among employees of the national medical research radiological centre of the ministry of health of the russian federation |
| topic | gastropanel medical workers helicobacter pylori atrophic gastritis esophagogastroduodenoscopy |
| url | https://www.gastro-j.ru/jour/article/view/922 |
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