Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye
The objectives of the study were to determine the aflatoxin M1 (AFM1) content in ınfant formula samples in Türkiye and to assess the risk of infants’ exposure to aflatoxins food contamination. A total number of 72 samples of infant formulas (premature, hipoallergenic, 0-6, 6-9,9-12 and 12-36 months)...
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Hasan Eleroğlu
2023-02-01
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| Series: | Turkish Journal of Agriculture: Food Science and Technology |
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| Online Access: | http://www.agrifoodscience.com/index.php/TURJAF/article/view/5805 |
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| author | Tuğba Demir Sema Ağaoğlu |
| author_facet | Tuğba Demir Sema Ağaoğlu |
| author_sort | Tuğba Demir |
| collection | DOAJ |
| description | The objectives of the study were to determine the aflatoxin M1 (AFM1) content in ınfant formula samples in Türkiye and to assess the risk of infants’ exposure to aflatoxins food contamination. A total number of 72 samples of infant formulas (premature, hipoallergenic, 0-6, 6-9,9-12 and 12-36 months) were analyzed for the presence of AFM1 using the Enzyme Linked Immunosorbent Assay (ELISA) method. 49% of the samples (35 samples) were contaminated with AFM1 and the group most highly contaminated with AFM1 was infant formulas 12-36 (8 samples) months. In addition, this study aimed at evaluating AFM1 levels especially above international (European Commission) (0.025 µg/kg) and local (Türkiye Food Codex Regulation) (0.025 µg/kg) standards and cancer risks associated with the ingestion of infant formula sampled from Türkiye. Five samples of infant formula had AFM1 concentration above maximum allowable concentration according to the standards. Risk assessments of AFM1 for infants ranged between 0.002- 0.035 ng/kg bw/day and >100.000–5263.15 respectively for Estimated Daily Intake (EDI), and Margin of Exposure (MOE). The riskiest group was determined in the 9-12 months samples. Results of our study indicate the high risk of infants’ exposure, who are at the early stage of development and vulnerable to toxic contaminants. |
| format | Article |
| id | doaj-art-a625ffd166c44e7c8a369bb5c4d331e9 |
| institution | DOAJ |
| issn | 2148-127X |
| language | English |
| publishDate | 2023-02-01 |
| publisher | Hasan Eleroğlu |
| record_format | Article |
| series | Turkish Journal of Agriculture: Food Science and Technology |
| spelling | doaj-art-a625ffd166c44e7c8a369bb5c4d331e92025-08-20T03:20:00ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2023-02-0111239640210.24925/turjaf.v11i2.396-402.58054551Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in TürkiyeTuğba Demir0https://orcid.org/0000-0002-5195-9372Sema Ağaoğlu1https://orcid.org/0000-0001-5252-8040Food Hygiene and Technology, Faculty of Veterinary, Sivas Cumhuriyet University, 58040 SivasFood Hygiene and Technology, Faculty of Veterinary, Sivas Cumhuriyet University, 58040 SivasThe objectives of the study were to determine the aflatoxin M1 (AFM1) content in ınfant formula samples in Türkiye and to assess the risk of infants’ exposure to aflatoxins food contamination. A total number of 72 samples of infant formulas (premature, hipoallergenic, 0-6, 6-9,9-12 and 12-36 months) were analyzed for the presence of AFM1 using the Enzyme Linked Immunosorbent Assay (ELISA) method. 49% of the samples (35 samples) were contaminated with AFM1 and the group most highly contaminated with AFM1 was infant formulas 12-36 (8 samples) months. In addition, this study aimed at evaluating AFM1 levels especially above international (European Commission) (0.025 µg/kg) and local (Türkiye Food Codex Regulation) (0.025 µg/kg) standards and cancer risks associated with the ingestion of infant formula sampled from Türkiye. Five samples of infant formula had AFM1 concentration above maximum allowable concentration according to the standards. Risk assessments of AFM1 for infants ranged between 0.002- 0.035 ng/kg bw/day and >100.000–5263.15 respectively for Estimated Daily Intake (EDI), and Margin of Exposure (MOE). The riskiest group was determined in the 9-12 months samples. Results of our study indicate the high risk of infants’ exposure, who are at the early stage of development and vulnerable to toxic contaminants.http://www.agrifoodscience.com/index.php/TURJAF/article/view/5805infant formulaaflatoxin m1estimated daily intakeexposure assessmentfood contamination |
| spellingShingle | Tuğba Demir Sema Ağaoğlu Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye Turkish Journal of Agriculture: Food Science and Technology infant formula aflatoxin m1 estimated daily intake exposure assessment food contamination |
| title | Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye |
| title_full | Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye |
| title_fullStr | Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye |
| title_full_unstemmed | Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye |
| title_short | Exposure Assessment of Aflatoxin M1 Through Ingestion of Infant Formula in Türkiye |
| title_sort | exposure assessment of aflatoxin m1 through ingestion of infant formula in turkiye |
| topic | infant formula aflatoxin m1 estimated daily intake exposure assessment food contamination |
| url | http://www.agrifoodscience.com/index.php/TURJAF/article/view/5805 |
| work_keys_str_mv | AT tugbademir exposureassessmentofaflatoxinm1throughingestionofinfantformulainturkiye AT semaagaoglu exposureassessmentofaflatoxinm1throughingestionofinfantformulainturkiye |