Nanocarriers Responsive to Light—A Review

The non-specific and minimally selective nature of traditional drug administration methods, along with various other limitations, makes the use of drug delivery systems more favorable. Light-responsive, or light-triggered, drug delivery systems provide more controlled and less invasive treatment app...

Full description

Saved in:
Bibliographic Details
Main Authors: Ismat F. Almadani, Mohammad F. Almadani, Nour AlSawaftah, Waad H. Abuwatfa, Ghaleb A. Husseini
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Micro
Subjects:
Online Access:https://www.mdpi.com/2673-8023/4/4/51
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846103666131468288
author Ismat F. Almadani
Mohammad F. Almadani
Nour AlSawaftah
Waad H. Abuwatfa
Ghaleb A. Husseini
author_facet Ismat F. Almadani
Mohammad F. Almadani
Nour AlSawaftah
Waad H. Abuwatfa
Ghaleb A. Husseini
author_sort Ismat F. Almadani
collection DOAJ
description The non-specific and minimally selective nature of traditional drug administration methods, along with various other limitations, makes the use of drug delivery systems more favorable. Light-responsive, or light-triggered, drug delivery systems provide more controlled and less invasive treatment approaches, addressing the shortcomings of traditional methods. In this paper, we reviewed studies utilizing light-triggered nanoparticles (NPs) for treating cancer and various other diseases, focusing on photodynamic therapy (PDT) and photothermal therapy (PTT) in both in vivo and in vitro applications. Most of the reviewed studies employed synergistic approaches that combined PDT or PTT with other therapeutic methods to leverage the strengths of both techniques and enhance treatment efficiency or to overcome the individual limitations of each method, which is discussed extensively in this paper.
format Article
id doaj-art-a60755a4455c4239bd5ef5f14c688b93
institution Kabale University
issn 2673-8023
language English
publishDate 2024-12-01
publisher MDPI AG
record_format Article
series Micro
spelling doaj-art-a60755a4455c4239bd5ef5f14c688b932024-12-27T14:40:22ZengMDPI AGMicro2673-80232024-12-014482784410.3390/micro4040051Nanocarriers Responsive to Light—A ReviewIsmat F. Almadani0Mohammad F. Almadani1Nour AlSawaftah2Waad H. Abuwatfa3Ghaleb A. Husseini4Biomedical Engineering Program, College of Engineering, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesFaculty of Medicine, Hashemite University, Zarqa 13133, JordanMaterials Science and Engineering Ph.D. Program, College of Arts and Sciences, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesMaterials Science and Engineering Ph.D. Program, College of Arts and Sciences, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesBiomedical Engineering Program, College of Engineering, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesThe non-specific and minimally selective nature of traditional drug administration methods, along with various other limitations, makes the use of drug delivery systems more favorable. Light-responsive, or light-triggered, drug delivery systems provide more controlled and less invasive treatment approaches, addressing the shortcomings of traditional methods. In this paper, we reviewed studies utilizing light-triggered nanoparticles (NPs) for treating cancer and various other diseases, focusing on photodynamic therapy (PDT) and photothermal therapy (PTT) in both in vivo and in vitro applications. Most of the reviewed studies employed synergistic approaches that combined PDT or PTT with other therapeutic methods to leverage the strengths of both techniques and enhance treatment efficiency or to overcome the individual limitations of each method, which is discussed extensively in this paper.https://www.mdpi.com/2673-8023/4/4/51drug deliverylight-responsivelight-triggerednanoparticlesnanocarriersphotodynamic therapy (PDT)
spellingShingle Ismat F. Almadani
Mohammad F. Almadani
Nour AlSawaftah
Waad H. Abuwatfa
Ghaleb A. Husseini
Nanocarriers Responsive to Light—A Review
Micro
drug delivery
light-responsive
light-triggered
nanoparticles
nanocarriers
photodynamic therapy (PDT)
title Nanocarriers Responsive to Light—A Review
title_full Nanocarriers Responsive to Light—A Review
title_fullStr Nanocarriers Responsive to Light—A Review
title_full_unstemmed Nanocarriers Responsive to Light—A Review
title_short Nanocarriers Responsive to Light—A Review
title_sort nanocarriers responsive to light a review
topic drug delivery
light-responsive
light-triggered
nanoparticles
nanocarriers
photodynamic therapy (PDT)
url https://www.mdpi.com/2673-8023/4/4/51
work_keys_str_mv AT ismatfalmadani nanocarriersresponsivetolightareview
AT mohammadfalmadani nanocarriersresponsivetolightareview
AT nouralsawaftah nanocarriersresponsivetolightareview
AT waadhabuwatfa nanocarriersresponsivetolightareview
AT ghalebahusseini nanocarriersresponsivetolightareview