Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery
[Objective:] To analyze the clinical value of preoperative blood inflammatory markers in diagnosing cervical lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC). [Methods:] A total of 141 TSCC patients who underwent surgical treatment in Henan Provincial People's Hospit...
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Editorial Office of Journal of Oral and Maxillofacial Surgery
2024-12-01
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| Series: | Kouqiang hemian waike zazhi |
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| Online Access: | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.06.006 |
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| author | CHENG Longlong ZHANG Shihan MENG Xin ZHANG Jingrui ZHOU Ying WANG Yonggong |
| author_facet | CHENG Longlong ZHANG Shihan MENG Xin ZHANG Jingrui ZHOU Ying WANG Yonggong |
| author_sort | CHENG Longlong |
| collection | DOAJ |
| description | [Objective:] To analyze the clinical value of preoperative blood inflammatory markers in diagnosing cervical lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC). [Methods:] A total of 141 TSCC patients who underwent surgical treatment in Henan Provincial People's Hospital from January 2017 to June 2023 were included. According to the postoperative pathological results, they were divided into cervical lymph node metastatic group and cervical lymph node non-metastatic group. The index of peripheral blood inflammatory cells (neutrophil, platelet, and lymphocyte count values) were collected from patients before surgery, and the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were calculated to analyze the value of preoperative NLR and PLR in diagnosing cervical lymph node metastasis in TSCC patients. [Results:] The NLR and PLR values in cervical lymph node metastatic group were significantly higher than those in the cervical lymph node non-metastatic group. The area under the curve (AUC) and optimal cutoff values for diagnosing cervical lymph node metastasis in TSCC patients using NLR and PLR are 0.72, 2.24 and 0.61, 115.43, respectively. Multivariate logistic regression analysis showed that NLR is an independent influencing factor for cervical lymph node metastasis in TSCC patients. [Conclusion:] The preoperative inflammatory marker NLR may be a potential biomarker for evaluating cervical lymph node metastasis in TSCC patients. |
| format | Article |
| id | doaj-art-a605c76353a242a19c3efabbe1dce5c3 |
| institution | Kabale University |
| issn | 1005-4979 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Journal of Oral and Maxillofacial Surgery |
| record_format | Article |
| series | Kouqiang hemian waike zazhi |
| spelling | doaj-art-a605c76353a242a19c3efabbe1dce5c32025-08-25T06:11:31ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792024-12-0134645345810.12439/kqhm.1005-4979.2024.06.006Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgeryCHENG Longlong0ZHANG Shihan1MENG Xin2ZHANG Jingrui3ZHOU Ying4WANG Yonggong5Henan University School of Stomatology, Kaifeng 475001Henan University School of Stomatology, Kaifeng 475001Henan University School of Stomatology, Kaifeng 475001Henan University School of Stomatology, Kaifeng 475001Department of Stomatology, Nanyang Second People's Hospital, Nanyang 473000, ChinaHenan University School of Stomatology, Kaifeng 475001[Objective:] To analyze the clinical value of preoperative blood inflammatory markers in diagnosing cervical lymph node metastasis in patients with tongue squamous cell carcinoma (TSCC). [Methods:] A total of 141 TSCC patients who underwent surgical treatment in Henan Provincial People's Hospital from January 2017 to June 2023 were included. According to the postoperative pathological results, they were divided into cervical lymph node metastatic group and cervical lymph node non-metastatic group. The index of peripheral blood inflammatory cells (neutrophil, platelet, and lymphocyte count values) were collected from patients before surgery, and the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were calculated to analyze the value of preoperative NLR and PLR in diagnosing cervical lymph node metastasis in TSCC patients. [Results:] The NLR and PLR values in cervical lymph node metastatic group were significantly higher than those in the cervical lymph node non-metastatic group. The area under the curve (AUC) and optimal cutoff values for diagnosing cervical lymph node metastasis in TSCC patients using NLR and PLR are 0.72, 2.24 and 0.61, 115.43, respectively. Multivariate logistic regression analysis showed that NLR is an independent influencing factor for cervical lymph node metastasis in TSCC patients. [Conclusion:] The preoperative inflammatory marker NLR may be a potential biomarker for evaluating cervical lymph node metastasis in TSCC patients.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.06.006tongue squamous cell carcinomaneutrophil to lymphocyte ratioplatelet to lymphocyte ratiocervical lymph node metastasis |
| spellingShingle | CHENG Longlong ZHANG Shihan MENG Xin ZHANG Jingrui ZHOU Ying WANG Yonggong Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery Kouqiang hemian waike zazhi tongue squamous cell carcinoma neutrophil to lymphocyte ratio platelet to lymphocyte ratio cervical lymph node metastasis |
| title | Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery |
| title_full | Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery |
| title_fullStr | Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery |
| title_full_unstemmed | Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery |
| title_short | Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery |
| title_sort | analysis of the diagnostic value of nlr and plr in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery |
| topic | tongue squamous cell carcinoma neutrophil to lymphocyte ratio platelet to lymphocyte ratio cervical lymph node metastasis |
| url | https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2024.06.006 |
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