Combined clinical and MRI-based radiomics model for predicting acute hematologic toxicity in gynecologic cancer radiotherapy

Combined clinical and MRI-based radiomics model for predicting acute hematologic toxicity in gynecologic cancer radiotherapy

Acute hematologic toxicity (HT) remains a critical dose-limiting complication in gynecologic cancer patients undergoing pelvic radiotherapy, particularly when combined with chemotherapy. Early prediction of severe HT could inform personalized management and minimize toxicity. We developed and valida...

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Bibliographic Details
Main Authors: Lumeng Luo, Jiahao Wang, Hongling Xie, Bingxin Chen, Hui Wang, Qiu Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
hematologic toxicity
radiomics
gynecologic cancer
magnetic resonance imaging
radiotherapy
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1644053/full
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