Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction

Abstract Background Distal radius fractures are a common orthopedic injury, particularly prevalent among elderly and osteoporotic patients. Although surgical treatment effectively restores fracture alignment and stabilizes the bone, Complex Regional Pain Syndrome (CRPS) can occur as a postoperative...

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Main Authors: Weipan Xu, Yue Liu, Bin Zhang, Junhua Ma
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Musculoskeletal Disorders
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Online Access:https://doi.org/10.1186/s12891-024-07948-3
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author Weipan Xu
Yue Liu
Bin Zhang
Junhua Ma
author_facet Weipan Xu
Yue Liu
Bin Zhang
Junhua Ma
author_sort Weipan Xu
collection DOAJ
description Abstract Background Distal radius fractures are a common orthopedic injury, particularly prevalent among elderly and osteoporotic patients. Although surgical treatment effectively restores fracture alignment and stabilizes the bone, Complex Regional Pain Syndrome (CRPS) can occur as a postoperative complication, severely impacting patients’ rehabilitation and quality of life. Therefore, assessing the risk factors for postoperative CRPS is crucial for early clinical intervention, aiming to improve recovery outcomes and overall patient well-being. Objective This study aims to dynamically evaluate the risk factors for CRPS following distal radius fracture surgery through a retrospective analysis. The goal is to provide scientific evidence for early clinical identification and intervention. Methods A retrospective analysis was conducted on 191 adult patients who underwent distal radius fracture surgery between January 2021 and December 2022, comprising 89 males and 102 females, with an average age of 59.7 ± 11.6(18–75) years. Baseline and follow-up data, including demographic information, clinical characteristics, and psychological assessments, were collected. Descriptive statistics, univariate, and multivariate logistic regression analyses were used to identify independent risk factors and assess their dynamic changes over time. Results Age, gender, occupation, fracture type, surgical method, osteoporosis, pain score (VAS), functional disability score (DASH), anxiety score (GAD-7), depression score (PHQ-9), physical therapy, and occupational therapy significantly affected the incidence of CRPS. Age and VAS scores were consistent risk factors. Female gender, internal fixation surgery, and high DASH scores posed higher risks in the early postoperative period but decreased over time. Occupation and fracture type were more significant in the mid to late postoperative period. Psychological factors were most significant in the midterm, while physical and occupational therapy were protective factors early on. Conclusion The occurrence of CRPS is the result of many factors. Elderly patients, females, and manual laborers had higher risks, with complex fractures and internal fixation surgery patients showing increased risk later on. Osteoporotic patients had higher risks in the mid to late postoperative period. VAS, DASH, GAD-7, and PHQ-9 scores were significantly associated with CRPS. Early physical and occupational therapy can effectively prevent CRPS, but further research is needed to evaluate their long-term effects.
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spelling doaj-art-a5feb357837942aeb9033cba29293fc82024-11-17T12:05:58ZengBMCBMC Musculoskeletal Disorders1471-24742024-11-0125111110.1186/s12891-024-07948-3Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and predictionWeipan Xu0Yue Liu1Bin Zhang2Junhua Ma3Shaoxing Hospital of Traditional Chinese MedicineShaoxing Hospital of Traditional Chinese MedicineShaoxing Hospital of Traditional Chinese MedicineShaoxing Hospital of Traditional Chinese MedicineAbstract Background Distal radius fractures are a common orthopedic injury, particularly prevalent among elderly and osteoporotic patients. Although surgical treatment effectively restores fracture alignment and stabilizes the bone, Complex Regional Pain Syndrome (CRPS) can occur as a postoperative complication, severely impacting patients’ rehabilitation and quality of life. Therefore, assessing the risk factors for postoperative CRPS is crucial for early clinical intervention, aiming to improve recovery outcomes and overall patient well-being. Objective This study aims to dynamically evaluate the risk factors for CRPS following distal radius fracture surgery through a retrospective analysis. The goal is to provide scientific evidence for early clinical identification and intervention. Methods A retrospective analysis was conducted on 191 adult patients who underwent distal radius fracture surgery between January 2021 and December 2022, comprising 89 males and 102 females, with an average age of 59.7 ± 11.6(18–75) years. Baseline and follow-up data, including demographic information, clinical characteristics, and psychological assessments, were collected. Descriptive statistics, univariate, and multivariate logistic regression analyses were used to identify independent risk factors and assess their dynamic changes over time. Results Age, gender, occupation, fracture type, surgical method, osteoporosis, pain score (VAS), functional disability score (DASH), anxiety score (GAD-7), depression score (PHQ-9), physical therapy, and occupational therapy significantly affected the incidence of CRPS. Age and VAS scores were consistent risk factors. Female gender, internal fixation surgery, and high DASH scores posed higher risks in the early postoperative period but decreased over time. Occupation and fracture type were more significant in the mid to late postoperative period. Psychological factors were most significant in the midterm, while physical and occupational therapy were protective factors early on. Conclusion The occurrence of CRPS is the result of many factors. Elderly patients, females, and manual laborers had higher risks, with complex fractures and internal fixation surgery patients showing increased risk later on. Osteoporotic patients had higher risks in the mid to late postoperative period. VAS, DASH, GAD-7, and PHQ-9 scores were significantly associated with CRPS. Early physical and occupational therapy can effectively prevent CRPS, but further research is needed to evaluate their long-term effects.https://doi.org/10.1186/s12891-024-07948-3Distal radius fractureComplex regional pain syndromeDynamic risk factorsMultivariate analysisEarly intervention
spellingShingle Weipan Xu
Yue Liu
Bin Zhang
Junhua Ma
Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction
BMC Musculoskeletal Disorders
Distal radius fracture
Complex regional pain syndrome
Dynamic risk factors
Multivariate analysis
Early intervention
title Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction
title_full Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction
title_fullStr Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction
title_full_unstemmed Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction
title_short Dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery: multivariate analysis and prediction
title_sort dynamic risk factors for complex regional pain syndrome after distal radius fracture surgery multivariate analysis and prediction
topic Distal radius fracture
Complex regional pain syndrome
Dynamic risk factors
Multivariate analysis
Early intervention
url https://doi.org/10.1186/s12891-024-07948-3
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