Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas

Introduction: Region specific epidemiological knowledge is needed to better help government and private entities plan and develop interventions to address accelerating diagnoses of Parkinson’s disease (PD). We measured the within-state prevalence patterns of PD within the state of Texas, United Stat...

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Main Authors: Sean G. Young, Kathryn Elwell, Christopher R. Watts
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Clinical Parkinsonism & Related Disorders
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590112525000738
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author Sean G. Young
Kathryn Elwell
Christopher R. Watts
author_facet Sean G. Young
Kathryn Elwell
Christopher R. Watts
author_sort Sean G. Young
collection DOAJ
description Introduction: Region specific epidemiological knowledge is needed to better help government and private entities plan and develop interventions to address accelerating diagnoses of Parkinson’s disease (PD). We measured the within-state prevalence patterns of PD within the state of Texas, United States, over a ten-year period to include factors of sex and race/ethnicity, with a specific focus on county and regional patterns. Methods: Publicly available data from the State of Texas Outpatient Public Use Data File (PUDF) evaluated for the years 2012 and 2022. Individuals with a PD specific diagnosis code were included. Age group, race, ethnicity, sex, and county of residence were used to calculate state and county case counts for the years 2012 and 2022. Spatial cluster analysis was applied to assess concentrations of diagnoses across Texas. Results: Prevalence rates of PD increased substantially in Texas from 2012 to 2022, especially among those aged 65 and older and Hispanics. Males had a higher prevalence rate in both years, though both sexes doubled their prevalence over the ten-year period. Spatial cluster analysis showed changes in diagnosis concentration, from the central and northeastern regions to the southwestern border region. Conclusion: Outpatient diagnoses of PD increased substantially from 2012 to 2022. Spatial distribution of PD risk evolved over the decade; such that risk for PD was greatest in the southwestern region of Texas in 2022 compared to all other areas. Prevalence trends in Texas mirror global trends for PD and should inform prevention and intervention strategies in the future.
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spelling doaj-art-a5f6e67517a3469aacf672228792dbbb2025-08-20T03:29:10ZengElsevierClinical Parkinsonism & Related Disorders2590-11252025-01-011310036910.1016/j.prdoa.2025.100369Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of TexasSean G. Young0Kathryn Elwell1Christopher R. Watts2Peter O’Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, United StatesPeter O’Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, United StatesHarris College of Nursing & Health Sciences, Texas Christian University, United States; Corresponding author at: Harris College of Nursing & Health Sciences, Texas Christian University, 2800 West Bowie St., Fort Worth, TX 76129, United States.Introduction: Region specific epidemiological knowledge is needed to better help government and private entities plan and develop interventions to address accelerating diagnoses of Parkinson’s disease (PD). We measured the within-state prevalence patterns of PD within the state of Texas, United States, over a ten-year period to include factors of sex and race/ethnicity, with a specific focus on county and regional patterns. Methods: Publicly available data from the State of Texas Outpatient Public Use Data File (PUDF) evaluated for the years 2012 and 2022. Individuals with a PD specific diagnosis code were included. Age group, race, ethnicity, sex, and county of residence were used to calculate state and county case counts for the years 2012 and 2022. Spatial cluster analysis was applied to assess concentrations of diagnoses across Texas. Results: Prevalence rates of PD increased substantially in Texas from 2012 to 2022, especially among those aged 65 and older and Hispanics. Males had a higher prevalence rate in both years, though both sexes doubled their prevalence over the ten-year period. Spatial cluster analysis showed changes in diagnosis concentration, from the central and northeastern regions to the southwestern border region. Conclusion: Outpatient diagnoses of PD increased substantially from 2012 to 2022. Spatial distribution of PD risk evolved over the decade; such that risk for PD was greatest in the southwestern region of Texas in 2022 compared to all other areas. Prevalence trends in Texas mirror global trends for PD and should inform prevention and intervention strategies in the future.http://www.sciencedirect.com/science/article/pii/S2590112525000738Parkinson’s diseaseEpidemiologyPrevalenceUnited States
spellingShingle Sean G. Young
Kathryn Elwell
Christopher R. Watts
Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas
Clinical Parkinsonism & Related Disorders
Parkinson’s disease
Epidemiology
Prevalence
United States
title Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas
title_full Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas
title_fullStr Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas
title_full_unstemmed Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas
title_short Regional changes in the prevalence of Parkinson’s disease over a ten-year period in the state of Texas
title_sort regional changes in the prevalence of parkinson s disease over a ten year period in the state of texas
topic Parkinson’s disease
Epidemiology
Prevalence
United States
url http://www.sciencedirect.com/science/article/pii/S2590112525000738
work_keys_str_mv AT seangyoung regionalchangesintheprevalenceofparkinsonsdiseaseoveratenyearperiodinthestateoftexas
AT kathrynelwell regionalchangesintheprevalenceofparkinsonsdiseaseoveratenyearperiodinthestateoftexas
AT christopherrwatts regionalchangesintheprevalenceofparkinsonsdiseaseoveratenyearperiodinthestateoftexas