Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan

Neuro-Behcet’s Disease (NBD) is a rare complication of Behcet’s Disease, being reported in approximately 5% of cases. This case study details a 36-year-old man with Behcet’s Disease who has developed acute neurological symptoms, including right arm weakness, vision disturbance, facial numbness, an...

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Main Authors: Rafi ullah, Arusa Lakhani
Format: Article
Language:English
Published: Liaquat National Hospital and Medical College 2025-04-01
Series:Journal of Liaquat National Hospital
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Online Access:https://journals.lnh.edu.pk/jlnh/pdf/d7256107-4123-4c04-bdd1-8ccc6d05c65f.pdf
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author Rafi ullah
Arusa Lakhani
author_facet Rafi ullah
Arusa Lakhani
author_sort Rafi ullah
collection DOAJ
description Neuro-Behcet’s Disease (NBD) is a rare complication of Behcet’s Disease, being reported in approximately 5% of cases. This case study details a 36-year-old man with Behcet’s Disease who has developed acute neurological symptoms, including right arm weakness, vision disturbance, facial numbness, and intermittent gait disturbance. The patient had a history of recurrent oral ulcers, genital ulcers and episodes of uveitis. Diagnostic imaging revealed characteristic findings such as perilesional vasogenic edema and nodular enhancement. Cerebrospinal fluid analysis showed elevated protein levels and neutrophils, consistent with NBD. However, the scarcity of screening and specific diagnostic tests makes it difficult to diagnose NBD in the early stage. Hence, it is realized that the complexities in NBD demand a multidisciplinary approach where advanced practice nurses, rheumatologists, neurologists, and infectious disease experts can work together to achieve early diagnosis and effective management for optimizing prognosis and enhancing the quality of life. This case also underscores the need for ongoing multispecialty care in the long-term management of NBD.
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spelling doaj-art-a5f394ba4e2541cc9abde2e9539dae6d2025-08-20T02:55:35ZengLiaquat National Hospital and Medical CollegeJournal of Liaquat National Hospital2959-18052960-29632025-04-0131515410.37184/jlnh.2959-1805.2.29Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from PakistanRafi ullah0Arusa Lakhani1Department of Nursing, Aga Khan School of Nursing and Midwifery, Karachi, PakistanDepartment of Nursing, Aga Khan School of Nursing and Midwifery, Karachi, PakistanNeuro-Behcet’s Disease (NBD) is a rare complication of Behcet’s Disease, being reported in approximately 5% of cases. This case study details a 36-year-old man with Behcet’s Disease who has developed acute neurological symptoms, including right arm weakness, vision disturbance, facial numbness, and intermittent gait disturbance. The patient had a history of recurrent oral ulcers, genital ulcers and episodes of uveitis. Diagnostic imaging revealed characteristic findings such as perilesional vasogenic edema and nodular enhancement. Cerebrospinal fluid analysis showed elevated protein levels and neutrophils, consistent with NBD. However, the scarcity of screening and specific diagnostic tests makes it difficult to diagnose NBD in the early stage. Hence, it is realized that the complexities in NBD demand a multidisciplinary approach where advanced practice nurses, rheumatologists, neurologists, and infectious disease experts can work together to achieve early diagnosis and effective management for optimizing prognosis and enhancing the quality of life. This case also underscores the need for ongoing multispecialty care in the long-term management of NBD.https://journals.lnh.edu.pk/jlnh/pdf/d7256107-4123-4c04-bdd1-8ccc6d05c65f.pdfneuro-behcet’s diseasebehcet’s diseasediagnostic challengesmulti-disciplinary approachdifferential diagnosis
spellingShingle Rafi ullah
Arusa Lakhani
Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan
Journal of Liaquat National Hospital
neuro-behcet’s disease
behcet’s disease
diagnostic challenges
multi-disciplinary approach
differential diagnosis
title Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan
title_full Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan
title_fullStr Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan
title_full_unstemmed Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan
title_short Challenges in Distinguishing Neuro-Behcets Disease from Other Neurological Conditions. A case report from Pakistan
title_sort challenges in distinguishing neuro behcets disease from other neurological conditions a case report from pakistan
topic neuro-behcet’s disease
behcet’s disease
diagnostic challenges
multi-disciplinary approach
differential diagnosis
url https://journals.lnh.edu.pk/jlnh/pdf/d7256107-4123-4c04-bdd1-8ccc6d05c65f.pdf
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