Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke

Ischemic stroke (CIS) is characterized by a high incidence, disability, and mortality. Numerous studies have demonstrated that intracranial arterial stenosis is an important pathological basis of CIS, and its main cause is atherosclerosis. Dyslipidemia is an important risk factor for atherosclerosis...

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Main Authors: Xinxu Chen, Xuefei Lu, Wei Li, Hongyan Zhang, Tan Wang
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2022/6403645
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author Xinxu Chen
Xuefei Lu
Wei Li
Hongyan Zhang
Tan Wang
author_facet Xinxu Chen
Xuefei Lu
Wei Li
Hongyan Zhang
Tan Wang
author_sort Xinxu Chen
collection DOAJ
description Ischemic stroke (CIS) is characterized by a high incidence, disability, and mortality. Numerous studies have demonstrated that intracranial arterial stenosis is an important pathological basis of CIS, and its main cause is atherosclerosis. Dyslipidemia is an important risk factor for atherosclerosis. Lysophosphatidic acid (Lpa), apolipoprotein -A(APO-A), and apolipoprotein -B(APO-B) proved to be significantly correlated with the severity of coronary artery disease. This study retrospectively collected the case data of 186 patients with CIS treated from May 2020 to May 2022 and explored the correlation between Lpa, APO-A, APO-B, and middle cerebral artery (MCA) stenosis in CIS patients.
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series Emergency Medicine International
spelling doaj-art-a5eb0ea83ab84412b91b1f383abb99d82025-02-03T05:57:54ZengWileyEmergency Medicine International2090-28592022-01-01202210.1155/2022/6403645Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic StrokeXinxu Chen0Xuefei Lu1Wei Li2Hongyan Zhang3Tan Wang4Department of NeurologyDepartment of AnesthesiologyDepartment of NeurologyDepartment of NeurologyDepartment of NeurologyIschemic stroke (CIS) is characterized by a high incidence, disability, and mortality. Numerous studies have demonstrated that intracranial arterial stenosis is an important pathological basis of CIS, and its main cause is atherosclerosis. Dyslipidemia is an important risk factor for atherosclerosis. Lysophosphatidic acid (Lpa), apolipoprotein -A(APO-A), and apolipoprotein -B(APO-B) proved to be significantly correlated with the severity of coronary artery disease. This study retrospectively collected the case data of 186 patients with CIS treated from May 2020 to May 2022 and explored the correlation between Lpa, APO-A, APO-B, and middle cerebral artery (MCA) stenosis in CIS patients.http://dx.doi.org/10.1155/2022/6403645
spellingShingle Xinxu Chen
Xuefei Lu
Wei Li
Hongyan Zhang
Tan Wang
Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke
Emergency Medicine International
title Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke
title_full Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke
title_fullStr Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke
title_full_unstemmed Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke
title_short Correlation between Lpa, APO-A, APO-B, and Stenosis of Middle Cerebral Artery in Patients with Cerebral Ischemic Stroke
title_sort correlation between lpa apo a apo b and stenosis of middle cerebral artery in patients with cerebral ischemic stroke
url http://dx.doi.org/10.1155/2022/6403645
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