Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy
Abstract Objectives Capsule endoscopy (CE) has been shown to have poor diagnostic performance when the capsule passes quickly through the small bowel, especially the proximal jejunum. This study aimed to evaluate the diagnostic yield of proximal jejunal lesions with third‐generation CE technology. M...
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Wiley
2023-04-01
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| Online Access: | https://doi.org/10.1002/deo2.134 |
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| author | Issei Hirata Akiyoshi Tsuboi Shiro Oka Akihiko Sumioka Sumio Iio Yuichi Hiyama Takahiro Kotachi Ryo Yuge Ryohei Hayashi Yuji Urabe Shinji Tanaka |
| author_facet | Issei Hirata Akiyoshi Tsuboi Shiro Oka Akihiko Sumioka Sumio Iio Yuichi Hiyama Takahiro Kotachi Ryo Yuge Ryohei Hayashi Yuji Urabe Shinji Tanaka |
| author_sort | Issei Hirata |
| collection | DOAJ |
| description | Abstract Objectives Capsule endoscopy (CE) has been shown to have poor diagnostic performance when the capsule passes quickly through the small bowel, especially the proximal jejunum. This study aimed to evaluate the diagnostic yield of proximal jejunal lesions with third‐generation CE technology. Methods We retrospectively examined 138 consecutive patients, 76 (55.0%) of whom were men. The patients’ median age was 70 years, and proximal jejunal lesions were detected by CE and/or double‐balloon endoscopy at Hiroshima University Hospital between January 2011 and June 2021. We analyzed the diagnostic accuracy of CE for proximal jejunal lesions and compared the characteristics of the discrepancy between the use of CE and double‐balloon endoscopy with Pillcam SB 2 (SB2) and Pillcam SB 3 (SB3). Results SB2 and SB3 were used in 48 (35%) and 90 (65%) patients, respectively. There was no difference in baseline characteristics between these groups. Small‐bowel lesions in the proximal jejunum comprised 75 tumors (54%), 50 vascular lesions (36%), and 13 inflammatory lesions (9%). The diagnostic rate was significantly higher in the SB3 group than in the SB2 group for tumors (91% vs. 72%, p < 0.05) and vascular lesions (97% vs. 69%, p < 0.01). For vascular lesions, in particular, the diagnostic rate of angioectasia improved in the SB3 group (100%) compared with that in the SB2 group (69%). Conclusions SB3 use improved the detection of proximal jejunal tumors and vascular lesions compared with SB2 use. |
| format | Article |
| id | doaj-art-a5e203b8b7f642ed99e6aee2ca2c401a |
| institution | OA Journals |
| issn | 2692-4609 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-a5e203b8b7f642ed99e6aee2ca2c401a2025-08-20T01:50:18ZengWileyDEN Open2692-46092023-04-0131n/an/a10.1002/deo2.134Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopyIssei Hirata0Akiyoshi Tsuboi1Shiro Oka2Akihiko Sumioka3Sumio Iio4Yuichi Hiyama5Takahiro Kotachi6Ryo Yuge7Ryohei Hayashi8Yuji Urabe9Shinji Tanaka10Department of Gastroenterology and Metabolism Hiroshima University Hospital Hiroshima JapanDepartment of Endoscopy Hiroshima University Hospital Hiroshima JapanDepartment of Gastroenterology and Metabolism Hiroshima University Hospital Hiroshima JapanDepartment of Gastroenterology and Metabolism Hiroshima University Hospital Hiroshima JapanDepartment of Gastroenterology and Metabolism Hiroshima University Hospital Hiroshima JapanDepartment of Center for Integrated Medical Research Hiroshima University Hospital Hiroshima JapanDepartment of Endoscopy Hiroshima University Hospital Hiroshima JapanDepartment of Endoscopy Hiroshima University Hospital Hiroshima JapanDepartment of Endoscopy Hiroshima University Hospital Hiroshima JapanDivision of Regeneration and Medicine Center for Translational and Clinical Research Hiroshima University Hospital Hiroshima JapanDepartment of Endoscopy Hiroshima University Hospital Hiroshima JapanAbstract Objectives Capsule endoscopy (CE) has been shown to have poor diagnostic performance when the capsule passes quickly through the small bowel, especially the proximal jejunum. This study aimed to evaluate the diagnostic yield of proximal jejunal lesions with third‐generation CE technology. Methods We retrospectively examined 138 consecutive patients, 76 (55.0%) of whom were men. The patients’ median age was 70 years, and proximal jejunal lesions were detected by CE and/or double‐balloon endoscopy at Hiroshima University Hospital between January 2011 and June 2021. We analyzed the diagnostic accuracy of CE for proximal jejunal lesions and compared the characteristics of the discrepancy between the use of CE and double‐balloon endoscopy with Pillcam SB 2 (SB2) and Pillcam SB 3 (SB3). Results SB2 and SB3 were used in 48 (35%) and 90 (65%) patients, respectively. There was no difference in baseline characteristics between these groups. Small‐bowel lesions in the proximal jejunum comprised 75 tumors (54%), 50 vascular lesions (36%), and 13 inflammatory lesions (9%). The diagnostic rate was significantly higher in the SB3 group than in the SB2 group for tumors (91% vs. 72%, p < 0.05) and vascular lesions (97% vs. 69%, p < 0.01). For vascular lesions, in particular, the diagnostic rate of angioectasia improved in the SB3 group (100%) compared with that in the SB2 group (69%). Conclusions SB3 use improved the detection of proximal jejunal tumors and vascular lesions compared with SB2 use.https://doi.org/10.1002/deo2.134capsule endoscopydiagnostic yielddouble‐balloon endoscopyproximal jejunumsmall‐bowel lesions |
| spellingShingle | Issei Hirata Akiyoshi Tsuboi Shiro Oka Akihiko Sumioka Sumio Iio Yuichi Hiyama Takahiro Kotachi Ryo Yuge Ryohei Hayashi Yuji Urabe Shinji Tanaka Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy DEN Open capsule endoscopy diagnostic yield double‐balloon endoscopy proximal jejunum small‐bowel lesions |
| title | Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy |
| title_full | Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy |
| title_fullStr | Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy |
| title_full_unstemmed | Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy |
| title_short | Diagnostic yield of proximal jejunal lesions with third‐generation capsule endoscopy |
| title_sort | diagnostic yield of proximal jejunal lesions with third generation capsule endoscopy |
| topic | capsule endoscopy diagnostic yield double‐balloon endoscopy proximal jejunum small‐bowel lesions |
| url | https://doi.org/10.1002/deo2.134 |
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