Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation
Conclusion: COS alleviates inflammation and platelet activation–mediated thrombosis in DN mice, potentially by inhibiting excessive NET formation. These findings highlight the therapeutic potential of COS in managing DN.
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/jdr/1159325 |
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| _version_ | 1849714721121370112 |
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| author | Xiangjing Wang Lina Zhang Ke Huang Chengli Lou Yuanying Xia Yijing Zhou |
| author_facet | Xiangjing Wang Lina Zhang Ke Huang Chengli Lou Yuanying Xia Yijing Zhou |
| author_sort | Xiangjing Wang |
| collection | DOAJ |
| description | Conclusion: COS alleviates inflammation and platelet activation–mediated thrombosis in DN mice, potentially by inhibiting excessive NET formation. These findings highlight the therapeutic potential of COS in managing DN. |
| format | Article |
| id | doaj-art-a5d3058e53ab4242b60de40c64ec11ff |
| institution | DOAJ |
| issn | 2314-6753 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-a5d3058e53ab4242b60de40c64ec11ff2025-08-20T03:13:38ZengWileyJournal of Diabetes Research2314-67532025-01-01202510.1155/jdr/1159325Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET FormationXiangjing Wang0Lina Zhang1Ke Huang2Chengli Lou3Yuanying Xia4Yijing Zhou5Department of NephrologyDepartment of General PracticeDepartment of NephrologyDepartment of NephrologyDepartment of NephrologyDepartment of NephrologyConclusion: COS alleviates inflammation and platelet activation–mediated thrombosis in DN mice, potentially by inhibiting excessive NET formation. These findings highlight the therapeutic potential of COS in managing DN.http://dx.doi.org/10.1155/jdr/1159325 |
| spellingShingle | Xiangjing Wang Lina Zhang Ke Huang Chengli Lou Yuanying Xia Yijing Zhou Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation Journal of Diabetes Research |
| title | Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation |
| title_full | Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation |
| title_fullStr | Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation |
| title_full_unstemmed | Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation |
| title_short | Costunolide Reduces DN Inflammatory Response and Renal Thrombosis by Inhibiting NET Formation |
| title_sort | costunolide reduces dn inflammatory response and renal thrombosis by inhibiting net formation |
| url | http://dx.doi.org/10.1155/jdr/1159325 |
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