Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection
Abstract In this work, a charge plasma TMD heterojunction tunnel FET-based dielectrically modulated biosensor is designed and investigated for biosensing applications. In the proposed biosensor, WTe2 and MoS2 serve as the source and channel material, respectively to form the heterojunction. Whereas...
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Nature Portfolio
2025-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-84677-6 |
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| author | Monika Kumari Niraj Kumar Singh Vinay Kantipudi Manodipan Sahoo |
| author_facet | Monika Kumari Niraj Kumar Singh Vinay Kantipudi Manodipan Sahoo |
| author_sort | Monika Kumari |
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| description | Abstract In this work, a charge plasma TMD heterojunction tunnel FET-based dielectrically modulated biosensor is designed and investigated for biosensing applications. In the proposed biosensor, WTe2 and MoS2 serve as the source and channel material, respectively to form the heterojunction. Whereas the channel-drain junction is a homojunction formed by MoS2. The advantage of heterojunction has been exploited to overcome the low I ON and ambipolar behavior of TFET, which results in the enhancement of sensitivity. The charge plasma doping has been utilized to mitigate random dopant variations, reduce manufacturing expenses, and simplify the fabrication process. Non-equilibrium green’s function (NEGF)-based simulator and SILVACO TCAD, a 2-D device simulator have been utilized to simulate the electrical characteristics of the proposed biosensor. Uniform filling of the cavities in biosensors is not always practically possible; thus, the issue of partial hybridization is also considered in this work. The proposed biosensor (for k = 9) achieves a high sensitivity of 1010, an I ON /I OFF ratio of 1014, and a low subthreshold swing of 39 mV/decade. Finally, the proposed biosensor is benchmarked with contemporary works of the literature and it has been observed that the presented charge plasma TMD heterojunction TFET (CP-TMD-HJ-TFET)-based biosensor has emerged to have a superior sensitivity (i.e. I ON /I OFF ratio) which is ∼ 4 decades higher than the maximum sensitivity reported by any contemporary biosensor. |
| format | Article |
| id | doaj-art-a5d01ff40e554340b68dc279abb6e46f |
| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-a5d01ff40e554340b68dc279abb6e46f2025-08-20T02:10:53ZengNature PortfolioScientific Reports2045-23222025-04-0115111410.1038/s41598-024-84677-6Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detectionMonika Kumari0Niraj Kumar Singh1Vinay Kantipudi2Manodipan Sahoo3Department of Electronics Engineering, Government PolytechnicDepartment of Electronics Engineering, Government PolytechnicDepartment of Electronics Engineering, Indian Institute of Technology (Indian School of Mines)Department of Electronics Engineering, Indian Institute of Technology (Indian School of Mines)Abstract In this work, a charge plasma TMD heterojunction tunnel FET-based dielectrically modulated biosensor is designed and investigated for biosensing applications. In the proposed biosensor, WTe2 and MoS2 serve as the source and channel material, respectively to form the heterojunction. Whereas the channel-drain junction is a homojunction formed by MoS2. The advantage of heterojunction has been exploited to overcome the low I ON and ambipolar behavior of TFET, which results in the enhancement of sensitivity. The charge plasma doping has been utilized to mitigate random dopant variations, reduce manufacturing expenses, and simplify the fabrication process. Non-equilibrium green’s function (NEGF)-based simulator and SILVACO TCAD, a 2-D device simulator have been utilized to simulate the electrical characteristics of the proposed biosensor. Uniform filling of the cavities in biosensors is not always practically possible; thus, the issue of partial hybridization is also considered in this work. The proposed biosensor (for k = 9) achieves a high sensitivity of 1010, an I ON /I OFF ratio of 1014, and a low subthreshold swing of 39 mV/decade. Finally, the proposed biosensor is benchmarked with contemporary works of the literature and it has been observed that the presented charge plasma TMD heterojunction TFET (CP-TMD-HJ-TFET)-based biosensor has emerged to have a superior sensitivity (i.e. I ON /I OFF ratio) which is ∼ 4 decades higher than the maximum sensitivity reported by any contemporary biosensor.https://doi.org/10.1038/s41598-024-84677-6 |
| spellingShingle | Monika Kumari Niraj Kumar Singh Vinay Kantipudi Manodipan Sahoo Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection Scientific Reports |
| title | Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection |
| title_full | Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection |
| title_fullStr | Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection |
| title_full_unstemmed | Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection |
| title_short | Design and investigation of charge plasma-based TMD heterojunction TFET biosensor for ultrasensitive detection |
| title_sort | design and investigation of charge plasma based tmd heterojunction tfet biosensor for ultrasensitive detection |
| url | https://doi.org/10.1038/s41598-024-84677-6 |
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