A narrative review on the effectiveness of PPSV23 vaccination in adults in China
Pneumococcal Polysaccharide Vaccine (PPSV23) is available for free in some Chinese cities for elderly patients and those with comorbidities. However, there is a lack of studies summarizing its preventive effect specifically in Chinese adults. This review aims to discuss the epidemiology of pneumococ...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2024.2440955 |
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| author | Weiyan Zhang Peng Bai Weijun Hu |
| author_facet | Weiyan Zhang Peng Bai Weijun Hu |
| author_sort | Weiyan Zhang |
| collection | DOAJ |
| description | Pneumococcal Polysaccharide Vaccine (PPSV23) is available for free in some Chinese cities for elderly patients and those with comorbidities. However, there is a lack of studies summarizing its preventive effect specifically in Chinese adults. This review aims to discuss the epidemiology of pneumococcal disease, coverage and effectiveness of PPSV23 vaccination, elderly individuals and patients with comorbidities, coadministration of PPSV23 vaccine with other vaccines, and future directions for its use in China. It was found that the PPSV23 vaccination rate among the elderly ranged from 1.2% to 42.1% depending on location, with an effectiveness of 9.34%(95%CI: 2.05%, 16.62%) to 57.7%(95%CI: 20.7%, 77.5%). There is a need to raise awareness of pneumococcal disease and its prevention, especially in China. To better manage pneumococcal disease in China, developing new vaccines for common serotypes and continuously monitoring serotype distribution associated with the disease is also needed. |
| format | Article |
| id | doaj-art-a5c444c57c0e474d96b141fc56cbfdcd |
| institution | DOAJ |
| issn | 2164-5515 2164-554X |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj-art-a5c444c57c0e474d96b141fc56cbfdcd2025-08-20T03:01:51ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2024.2440955A narrative review on the effectiveness of PPSV23 vaccination in adults in ChinaWeiyan Zhang0Peng Bai1Weijun Hu2Shandong Provincial Center for Disease Control and Prevention, Jinan, Shandong, ChinaValue & Implementation Global Medical & Scientific Affairs, MSD China, Shanghai, Jiangsu, ChinaShaanxi Provincial Center for Disease Control and Prevention, Xi’an, Shaanxi, ChinaPneumococcal Polysaccharide Vaccine (PPSV23) is available for free in some Chinese cities for elderly patients and those with comorbidities. However, there is a lack of studies summarizing its preventive effect specifically in Chinese adults. This review aims to discuss the epidemiology of pneumococcal disease, coverage and effectiveness of PPSV23 vaccination, elderly individuals and patients with comorbidities, coadministration of PPSV23 vaccine with other vaccines, and future directions for its use in China. It was found that the PPSV23 vaccination rate among the elderly ranged from 1.2% to 42.1% depending on location, with an effectiveness of 9.34%(95%CI: 2.05%, 16.62%) to 57.7%(95%CI: 20.7%, 77.5%). There is a need to raise awareness of pneumococcal disease and its prevention, especially in China. To better manage pneumococcal disease in China, developing new vaccines for common serotypes and continuously monitoring serotype distribution associated with the disease is also needed.https://www.tandfonline.com/doi/10.1080/21645515.2024.2440955Chinaelderlypneumococcal polysaccharidevaccineeffectiveness |
| spellingShingle | Weiyan Zhang Peng Bai Weijun Hu A narrative review on the effectiveness of PPSV23 vaccination in adults in China Human Vaccines & Immunotherapeutics China elderly pneumococcal polysaccharide vaccine effectiveness |
| title | A narrative review on the effectiveness of PPSV23 vaccination in adults in China |
| title_full | A narrative review on the effectiveness of PPSV23 vaccination in adults in China |
| title_fullStr | A narrative review on the effectiveness of PPSV23 vaccination in adults in China |
| title_full_unstemmed | A narrative review on the effectiveness of PPSV23 vaccination in adults in China |
| title_short | A narrative review on the effectiveness of PPSV23 vaccination in adults in China |
| title_sort | narrative review on the effectiveness of ppsv23 vaccination in adults in china |
| topic | China elderly pneumococcal polysaccharide vaccine effectiveness |
| url | https://www.tandfonline.com/doi/10.1080/21645515.2024.2440955 |
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