Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia

<p> <b>A.B. Movsisyan<sup>1,2</sup>, A.V. Kuroedov<sup>1,3</sup>, M.A. Arkharov<sup>4</sup>, V.V. Prokhorenko<sup>4</sup>, I.A.Chepurnov<sup>4</sup></b> </p> <p> <b><sup>1</sup>Pirogov Russi...

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Main Authors: A.B. Movsisyan, A.V. Kuroyedov, M.A. Arkharov, V.V. Prokhorenko, I.A.Chepurnov
Format: Article
Language:Russian
Published: Prime-Media 2022-02-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/9f0/9f008fc546a588e01aa0334b8507d36f.pdf
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author A.B. Movsisyan
A.V. Kuroyedov
M.A. Arkharov
V.V. Prokhorenko
I.A.Chepurnov
author_facet A.B. Movsisyan
A.V. Kuroyedov
M.A. Arkharov
V.V. Prokhorenko
I.A.Chepurnov
author_sort A.B. Movsisyan
collection DOAJ
description <p> <b>A.B. Movsisyan<sup>1,2</sup>, A.V. Kuroedov<sup>1,3</sup>, M.A. Arkharov<sup>4</sup>, V.V. Prokhorenko<sup>4</sup>, I.A.Chepurnov<sup>4</sup></b> </p> <p> <b><sup>1</sup>Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <b><sup>2</sup>Hospital for War Veterans No. 2, Moscow, Russian Federation</b> </p> <p> <b><sup>3</sup>P.V. Mandryka Military Clinical Hospital, Moscow, Russian Federation</b> </p> <p> <b><sup>4</sup>N.E. Bauman Moscow State Technical University, Moscow, Russian Federation</b> </p> <p> <i><b>Background</b>: more than 50% of newly diagnosed primary open-angle glaucoma (POAG) patients are in the moderate or advanced stages. It&nbsp;is&nbsp;difficult to assess disease course due to limited official data. On a national scale, prevalence and incidence are measures that hardly provide a complete "landscape" of this issue in Russia.</i> </p> <p> <i><b>Aim</b>: to determine the prognosis of changes in epidemiological indicators (prevalence and incidence) of POAG in Russia, assess disease duration and calculate presumed age of disease onset.</i> </p> <p> <i><b>Patients and Methods:</b> we applied a scientific-analytical design implying literary statistical analysis of official epidemiological indicators of&nbsp;glaucoma in Russia and multicenter trials. These data were a basis for prediction (three variants) of glaucoma incidence and prevalence in&nbsp;Russia and the development of a mathematical model to determine the age of disease onset and duration.</i> </p> <p> <i><b>Results</b>: the age of patients with POAG stage 0 was 54 (49;58) yea rs. This age was calculated based on data from publications in 2000–2016. These data were initially used to calculate the mean duration of each glaucoma stage. As a result, the "true" age of stage 1 onset was 57&nbsp;(52;61) years. Meanwhile, the mean age of stage 1 diagnosis was 60 (56;65) years. According to these calculations and considering predicted changes in population size and average life expectancy, a growth in glaucoma incidence and prevalence is expected in low, medium, and high population projections.</i> </p> <p> <i><b>Conclusions</b>: we demonstrated an expected growth in glaucoma incidence and prevalence in Russia in the coming 15 years. An increase in&nbsp;visual disability and, therefore, rapid loss of working capacity in various age groups due to "late" diagnosis and treatment are also likely. Collection of epidemiological data, further analysis of these findings, and searching for ways to improve diagnosis and course of socially significant diseases (e.g., glaucoma) are among strate gic tasks for the healthcare system.</i> </p> <p> <i><b>Keywords</b>: primary open-angle glaucoma, glaucoma diagnosis, glaucoma epidemiology, prognosis.</i> </p> <p> <i><b>For citation:</b> Movsisyan A.B., Kuroedov A.V., Arkharov M.A. et al. Epidemiological analysis primary open-angle glaucoma incidence&nbsp;and prevalence in Russia. Russian Journal of Clinical Ophthalmology. 2022;22(1):3–10 (in Russ.). DOI: 10.32364/2311-7729-2022-22-1-3-10.</i> </p>
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spelling doaj-art-a5c138f7e7214cbeb3bf0ab78e95ec4e2025-01-16T09:39:37ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712022-02-0122131425Epidemiological analysis primary open-angle glaucoma incidence and prevalence in RussiaA.B. Movsisyan0A.V. Kuroyedov1M.A. Arkharov2V.V. Prokhorenko3I.A.Chepurnov4Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<p> <b>A.B. Movsisyan<sup>1,2</sup>, A.V. Kuroedov<sup>1,3</sup>, M.A. Arkharov<sup>4</sup>, V.V. Prokhorenko<sup>4</sup>, I.A.Chepurnov<sup>4</sup></b> </p> <p> <b><sup>1</sup>Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <b><sup>2</sup>Hospital for War Veterans No. 2, Moscow, Russian Federation</b> </p> <p> <b><sup>3</sup>P.V. Mandryka Military Clinical Hospital, Moscow, Russian Federation</b> </p> <p> <b><sup>4</sup>N.E. Bauman Moscow State Technical University, Moscow, Russian Federation</b> </p> <p> <i><b>Background</b>: more than 50% of newly diagnosed primary open-angle glaucoma (POAG) patients are in the moderate or advanced stages. It&nbsp;is&nbsp;difficult to assess disease course due to limited official data. On a national scale, prevalence and incidence are measures that hardly provide a complete "landscape" of this issue in Russia.</i> </p> <p> <i><b>Aim</b>: to determine the prognosis of changes in epidemiological indicators (prevalence and incidence) of POAG in Russia, assess disease duration and calculate presumed age of disease onset.</i> </p> <p> <i><b>Patients and Methods:</b> we applied a scientific-analytical design implying literary statistical analysis of official epidemiological indicators of&nbsp;glaucoma in Russia and multicenter trials. These data were a basis for prediction (three variants) of glaucoma incidence and prevalence in&nbsp;Russia and the development of a mathematical model to determine the age of disease onset and duration.</i> </p> <p> <i><b>Results</b>: the age of patients with POAG stage 0 was 54 (49;58) yea rs. This age was calculated based on data from publications in 2000–2016. These data were initially used to calculate the mean duration of each glaucoma stage. As a result, the "true" age of stage 1 onset was 57&nbsp;(52;61) years. Meanwhile, the mean age of stage 1 diagnosis was 60 (56;65) years. According to these calculations and considering predicted changes in population size and average life expectancy, a growth in glaucoma incidence and prevalence is expected in low, medium, and high population projections.</i> </p> <p> <i><b>Conclusions</b>: we demonstrated an expected growth in glaucoma incidence and prevalence in Russia in the coming 15 years. An increase in&nbsp;visual disability and, therefore, rapid loss of working capacity in various age groups due to "late" diagnosis and treatment are also likely. Collection of epidemiological data, further analysis of these findings, and searching for ways to improve diagnosis and course of socially significant diseases (e.g., glaucoma) are among strate gic tasks for the healthcare system.</i> </p> <p> <i><b>Keywords</b>: primary open-angle glaucoma, glaucoma diagnosis, glaucoma epidemiology, prognosis.</i> </p> <p> <i><b>For citation:</b> Movsisyan A.B., Kuroedov A.V., Arkharov M.A. et al. Epidemiological analysis primary open-angle glaucoma incidence&nbsp;and prevalence in Russia. Russian Journal of Clinical Ophthalmology. 2022;22(1):3–10 (in Russ.). DOI: 10.32364/2311-7729-2022-22-1-3-10.</i> </p>http://clinopht.com/upload/iblock/9f0/9f008fc546a588e01aa0334b8507d36f.pdf
spellingShingle A.B. Movsisyan
A.V. Kuroyedov
M.A. Arkharov
V.V. Prokhorenko
I.A.Chepurnov
Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
РМЖ "Клиническая офтальмология"
title Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
title_full Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
title_fullStr Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
title_full_unstemmed Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
title_short Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
title_sort epidemiological analysis primary open angle glaucoma incidence and prevalence in russia
url http://clinopht.com/upload/iblock/9f0/9f008fc546a588e01aa0334b8507d36f.pdf
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AT maarkharov epidemiologicalanalysisprimaryopenangleglaucomaincidenceandprevalenceinrussia
AT vvprokhorenko epidemiologicalanalysisprimaryopenangleglaucomaincidenceandprevalenceinrussia
AT iachepurnov epidemiologicalanalysisprimaryopenangleglaucomaincidenceandprevalenceinrussia