Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases
This review explores the impact of physical exercise on brain-derived neurotrophic factor (BDNF) and its relationship with neurodegenerative diseases. The key role of BDNF in maintaining brain health is highlighted, and recent studies are analyzed that indicate an increase in BDNF levels following p...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1505879/full |
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| author | Ana Romero Garavito Valery Díaz Martínez Estherz Juárez Cortés José Vicente Negrete Díaz José Vicente Negrete Díaz Liliana Marcela Montilla Rodríguez |
| author_facet | Ana Romero Garavito Valery Díaz Martínez Estherz Juárez Cortés José Vicente Negrete Díaz José Vicente Negrete Díaz Liliana Marcela Montilla Rodríguez |
| author_sort | Ana Romero Garavito |
| collection | DOAJ |
| description | This review explores the impact of physical exercise on brain-derived neurotrophic factor (BDNF) and its relationship with neurodegenerative diseases. The key role of BDNF in maintaining brain health is highlighted, and recent studies are analyzed that indicate an increase in BDNF levels following physical activity, particularly in young adults. Additionally, the interaction between the BDNF Val66Met genetic polymorphism and exercise on cognitive function is examined. The review emphasizes the possibility of exercise as a complementary therapy for neurodegenerative diseases, although further research is required to fully understand its effects. |
| format | Article |
| id | doaj-art-a5b7499c8c7c48a6bff6407fb0fffea7 |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-a5b7499c8c7c48a6bff6407fb0fffea72025-01-28T05:10:31ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-01-011510.3389/fneur.2024.15058791505879Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseasesAna Romero Garavito0Valery Díaz Martínez1Estherz Juárez Cortés2José Vicente Negrete Díaz3José Vicente Negrete Díaz4Liliana Marcela Montilla Rodríguez5Facultad de medicina, Universidad Cooperativa de Colombia, Villavicencio, ColombiaFacultad de medicina, Universidad Cooperativa de Colombia, Villavicencio, ColombiaPrograma de Fisioterapia, Universidad de Guanajuato, Guanajuato, MexicoPrograma de Fisioterapia, Universidad de Guanajuato, Guanajuato, MexicoPrograma de Psicologia Clinica, Universidad de Guanajuato, Guanajuato, MexicoFacultad de medicina, Universidad Cooperativa de Colombia, Villavicencio, ColombiaThis review explores the impact of physical exercise on brain-derived neurotrophic factor (BDNF) and its relationship with neurodegenerative diseases. The key role of BDNF in maintaining brain health is highlighted, and recent studies are analyzed that indicate an increase in BDNF levels following physical activity, particularly in young adults. Additionally, the interaction between the BDNF Val66Met genetic polymorphism and exercise on cognitive function is examined. The review emphasizes the possibility of exercise as a complementary therapy for neurodegenerative diseases, although further research is required to fully understand its effects.https://www.frontiersin.org/articles/10.3389/fneur.2024.1505879/fullphysical exercisebrain-derived neurotrophic factor (BDNF)neurodegenerative diseasesdementiaParkinson’s diseaseneuroplasticity |
| spellingShingle | Ana Romero Garavito Valery Díaz Martínez Estherz Juárez Cortés José Vicente Negrete Díaz José Vicente Negrete Díaz Liliana Marcela Montilla Rodríguez Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases Frontiers in Neurology physical exercise brain-derived neurotrophic factor (BDNF) neurodegenerative diseases dementia Parkinson’s disease neuroplasticity |
| title | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| title_full | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| title_fullStr | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| title_full_unstemmed | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| title_short | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| title_sort | impact of physical exercise on the regulation of brain derived neurotrophic factor in people with neurodegenerative diseases |
| topic | physical exercise brain-derived neurotrophic factor (BDNF) neurodegenerative diseases dementia Parkinson’s disease neuroplasticity |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1505879/full |
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