Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus
Fullyhuman antibodies have a great therapeutic importance; however, the development of stable strains providing a high level of production of fullsize antibodies is a challenging task, as antibody molecules contain two types of polypeptide chains. To develop the producing strain, random integratio...
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Main Authors: | A. L. Matveev, Ya. A. Khlusevich, I. K. Baykov, I. V. Babkin, E. P. Goncharova, V. V. Morozova, N. V. Tikunova |
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Format: | Article |
Language: | English |
Published: |
Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2018-01-01
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Series: | Вавиловский журнал генетики и селекции |
Subjects: | |
Online Access: | https://vavilov.elpub.ru/jour/article/view/1279 |
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