Very low urinary marinobufagenin excretion reflects a high risk of disease progression in non-advanced CKD

Very low urinary marinobufagenin excretion reflects a high risk of disease progression in non-advanced CKD

BackgroundChronic kidney disease (CKD) has now reached pandemic proportions but risk prediction towards end-stage kidney disease (ESKD) remains challenging. Kidney fibrosis is a key determinant in the transition from CKD to ESKD. In this prospective study, we investigated the prognostic significance...

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Main Authors: Davide Bolignano, Marta Greco, Loredana Tripodi, Mario D’Agostino, Paola Cianfrone, Roberta Misiti, Sara Pugliese, Mariateresa Zicarelli, Michela Musolino, Daniela Patrizia Foti, Michele Andreucci, Giuseppe Coppolino
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Physiology
Subjects:
chronic kidney disease
CKD progression
biomarker
marinobufagenin
renal failure
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1527805/full
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