A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology
Herpes simplex virus-2 (HSV2) hepatitis represents a rare but serious complication of HSV2 infection that can progress to acute liver failure (ALF). We describe a case of a pregnant teenager who presented with four days of fever, headache, malaise, nausea, and vomiting. She was initially misdiagnose...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2019/4808143 |
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| author | Mohanad Soliman Olalekan Akanbi Ihab Almagdub Kishore Karri Pradeep Yarra Saad Emhmed Ali Hanine El Haddad |
| author_facet | Mohanad Soliman Olalekan Akanbi Ihab Almagdub Kishore Karri Pradeep Yarra Saad Emhmed Ali Hanine El Haddad |
| author_sort | Mohanad Soliman |
| collection | DOAJ |
| description | Herpes simplex virus-2 (HSV2) hepatitis represents a rare but serious complication of HSV2 infection that can progress to acute liver failure (ALF). We describe a case of a pregnant teenager who presented with four days of fever, headache, malaise, nausea, and vomiting. She was initially misdiagnosed with sepsis of unclear source and treated with broad-spectrum antibiotics. Empiric acyclovir was started one week into her hospitalization despite negative serologies while awaiting HSV2 PCR leading to complete resolution of symptoms. Given its high mortality and nonspecific presentation, clinicians should consider HSV hepatitis in all patients with acute hepatitis especially in high-risk population. |
| format | Article |
| id | doaj-art-a595d46517df41669ea1f2975a2d0aaf |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-a595d46517df41669ea1f2975a2d0aaf2025-02-03T01:10:20ZengWileyCase Reports in Hepatology2090-65872090-65952019-01-01201910.1155/2019/48081434808143A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative SerologyMohanad Soliman0Olalekan Akanbi1Ihab Almagdub2Kishore Karri3Pradeep Yarra4Saad Emhmed Ali5Hanine El Haddad6Department of Medicine, Division of Hospital Medicine, University of Kentucky, Lexington, KY, USADepartment of Medicine, Division of Hospital Medicine, University of Kentucky, Lexington, KY, USADepartment of Medicine, Division of Hospital Medicine, University of Kentucky, Lexington, KY, USADepartment of Medicine, Division of Hospital Medicine, University of Kentucky, Lexington, KY, USADepartment of Medicine, Division of Hospital Medicine, University of Kentucky, Lexington, KY, USADepartment of Medicine, Division of Hospital Medicine, University of Kentucky, Lexington, KY, USADepartment of Medicine, Division of Infectious Diseases, University of Kentucky, Lexington, KY, USAHerpes simplex virus-2 (HSV2) hepatitis represents a rare but serious complication of HSV2 infection that can progress to acute liver failure (ALF). We describe a case of a pregnant teenager who presented with four days of fever, headache, malaise, nausea, and vomiting. She was initially misdiagnosed with sepsis of unclear source and treated with broad-spectrum antibiotics. Empiric acyclovir was started one week into her hospitalization despite negative serologies while awaiting HSV2 PCR leading to complete resolution of symptoms. Given its high mortality and nonspecific presentation, clinicians should consider HSV hepatitis in all patients with acute hepatitis especially in high-risk population.http://dx.doi.org/10.1155/2019/4808143 |
| spellingShingle | Mohanad Soliman Olalekan Akanbi Ihab Almagdub Kishore Karri Pradeep Yarra Saad Emhmed Ali Hanine El Haddad A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology Case Reports in Hepatology |
| title | A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology |
| title_full | A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology |
| title_fullStr | A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology |
| title_full_unstemmed | A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology |
| title_short | A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology |
| title_sort | rare case of herpes simplex virus 2 hepatitis with negative serology |
| url | http://dx.doi.org/10.1155/2019/4808143 |
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