Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy

Nowadays, due to improvements in living standards, more attention is reserved to all-around disease prevention and health care. In particular, research efforts have been made for developing novel methods and treatments for anti-cancer therapy. Self-powered nanogenerators have emerged in recent years...

Full description

Saved in:
Bibliographic Details
Main Author: Massimo Mariello
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Nanoenergy Advances
Subjects:
Online Access:https://www.mdpi.com/2673-706X/5/2/4
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849704938077159424
author Massimo Mariello
author_facet Massimo Mariello
author_sort Massimo Mariello
collection DOAJ
description Nowadays, due to improvements in living standards, more attention is reserved to all-around disease prevention and health care. In particular, research efforts have been made for developing novel methods and treatments for anti-cancer therapy. Self-powered nanogenerators have emerged in recent years as an attractive cost-effective technology to harvest energy or for biosensing applications. Bioelectronic nanogenerators can be used for inducing tissue recovery and for treating human illness through electrical stimulation. However, there is still a lack of comprehensive cognitive assessment of these devices and platforms, especially regarding which requirements must be satisfied and which working principles for energy transduction can be adopted effectively in the body. This review covers the most recent advances in bioelectronic nanogenerators for anti-cancer therapy, based on different transducing strategies (photodynamic therapy, drug delivery, electrical stimulation, atomic nanogenerators, etc.), and the potential mechanisms for tissue repair promotion are discussed. The prospective challenges are finally summarized with an indication of a future outlook.
format Article
id doaj-art-a5928441a63b43faae6a9ee2ceacb217
institution DOAJ
issn 2673-706X
language English
publishDate 2025-03-01
publisher MDPI AG
record_format Article
series Nanoenergy Advances
spelling doaj-art-a5928441a63b43faae6a9ee2ceacb2172025-08-20T03:16:35ZengMDPI AGNanoenergy Advances2673-706X2025-03-0152410.3390/nanoenergyadv5020004Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer TherapyMassimo Mariello0Department of Engineering for Innovation, Università del Salento, 73100 Lecce, ItalyNowadays, due to improvements in living standards, more attention is reserved to all-around disease prevention and health care. In particular, research efforts have been made for developing novel methods and treatments for anti-cancer therapy. Self-powered nanogenerators have emerged in recent years as an attractive cost-effective technology to harvest energy or for biosensing applications. Bioelectronic nanogenerators can be used for inducing tissue recovery and for treating human illness through electrical stimulation. However, there is still a lack of comprehensive cognitive assessment of these devices and platforms, especially regarding which requirements must be satisfied and which working principles for energy transduction can be adopted effectively in the body. This review covers the most recent advances in bioelectronic nanogenerators for anti-cancer therapy, based on different transducing strategies (photodynamic therapy, drug delivery, electrical stimulation, atomic nanogenerators, etc.), and the potential mechanisms for tissue repair promotion are discussed. The prospective challenges are finally summarized with an indication of a future outlook.https://www.mdpi.com/2673-706X/5/2/4nanogeneratorsanti-cancer therapytumorpiezoelectrictriboelectricpyroelectric
spellingShingle Massimo Mariello
Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
Nanoenergy Advances
nanogenerators
anti-cancer therapy
tumor
piezoelectric
triboelectric
pyroelectric
title Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
title_full Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
title_fullStr Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
title_full_unstemmed Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
title_short Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
title_sort advances and perspectives on bioelectronic and atomic nanogenerators for anticancer therapy
topic nanogenerators
anti-cancer therapy
tumor
piezoelectric
triboelectric
pyroelectric
url https://www.mdpi.com/2673-706X/5/2/4
work_keys_str_mv AT massimomariello advancesandperspectivesonbioelectronicandatomicnanogeneratorsforanticancertherapy