Differential function of Themis CABIT domains during T cell development.

Differential function of Themis CABIT domains during T cell development.

Themis (also named Gasp) is a newly identified Grb2-binding protein that is essential for thymocyte positive selection. Despite the possible involvement of Themis in TCR-mediated signal transduction, its function remains unresolved and controversial. Themis contains two functionally uncharacterized...

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Bibliographic Details
Main Authors: Toshiyuki Okada, Takeshi Nitta, Kentaro Kaji, Akiko Takashima, Hiroyo Oda, Norimasa Tamehiro, Motohito Goto, Tadashi Okamura, Michael S Patrick, Harumi Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089115&type=printable
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