Rapid-onset cancer

Human cancers are generally thought to develop over the course of decades. Such slow progression is well documented for a variety of cancers that we designate “slow-onset” cancers. “Rapid-onset” cancers, in contrast, can develop in a matter of months in humans or in as little as 9 days in mice. Thes...

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Bibliographic Details
Main Authors: Andrea Bilger, Paul F. Lambert
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Tumour Virus Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666679024000363
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Summary:Human cancers are generally thought to develop over the course of decades. Such slow progression is well documented for a variety of cancers that we designate “slow-onset” cancers. “Rapid-onset” cancers, in contrast, can develop in a matter of months in humans or in as little as 9 days in mice. These cancers often develop under conditions that might be expected to accelerate cancer development: early development, immune deficiency, or viral infection. We will discuss rapid-onset cancers in the context of the ''hallmarks of cancer'' – properties cells must acquire in order to become malignant – focusing on how viruses are particularly well suited to causing rapid-onset cancer.
ISSN:2666-6790