Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease
Purpose: This study aimed to assess the styloid process (TBSP) phenotype and to identify suggestive images of calcified atheromatous plaques (CAP) in panoramic radiographs of patients with primary hyperparathyroidism (PHPT) and post-surgical hypoparathyroidism (hypoPT). Additionally, it aimed to ana...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426824001775 |
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| author | Adilia Mirela Pereira Lima Cid Davi de Sá Cavalcante Marcela Lima Gurgel Ana Carolina Saraiva Ana Alicia Sales Ricardo Lúcio Mitsuo Kurita Paulo Goberlânio de Barros Silva Catarina Brasil d’Alva Ana Rosa Pinto Quidute Fabio Wildson Gurgel Costa |
| author_facet | Adilia Mirela Pereira Lima Cid Davi de Sá Cavalcante Marcela Lima Gurgel Ana Carolina Saraiva Ana Alicia Sales Ricardo Lúcio Mitsuo Kurita Paulo Goberlânio de Barros Silva Catarina Brasil d’Alva Ana Rosa Pinto Quidute Fabio Wildson Gurgel Costa |
| author_sort | Adilia Mirela Pereira Lima Cid |
| collection | DOAJ |
| description | Purpose: This study aimed to assess the styloid process (TBSP) phenotype and to identify suggestive images of calcified atheromatous plaques (CAP) in panoramic radiographs of patients with primary hyperparathyroidism (PHPT) and post-surgical hypoparathyroidism (hypoPT). Additionally, it aimed to analyze the association between the bone mineral status of patients with parathyroid diseases and the radiographic findings. Material and methods: A cross-sectional case-control study was conducted with individuals diagnosed with PHPT (n = 25) and post-surgical hypoPT (n = 25). A control group (n = 50) comprised individuals without parathyroid gland disorders. Panoramic radiographs were utilized for both quantitative (length) and qualitative (mineralization patterns) evaluation of the TBSP, as well as for assessing the prevalence of CAP. Results: The frequency of TBSP exceeding 30 mm was significantly higher in the PHPT and post-surgical hypoPT groups compared to the control group. CAP occurred more frequently in the PHPT group. Cases of low bone mineral density (BMD) were associated with PHPT. In the PHPT group, low BMD was linked to an increased average TBSP length (p = 0.025) and a higher frequency of elongated TBSP (p = 0.022). Multivariate analysis revealed an inverse relationship between the T-score of the femoral neck and TBSP length in the PHPT group (p = 0.028). Conclusions: Compared to the control group, individuals with PHPT and post-surgical hypoPT showed distinct imaging findings related to TBSP and CAP. Individuals with PHPT and low BMD showed a higher frequency of elongated TBSP. |
| format | Article |
| id | doaj-art-a58adbc63ace41b4bb948d21a2cd1a17 |
| institution | Kabale University |
| issn | 2212-4268 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-a58adbc63ace41b4bb948d21a2cd1a172025-02-09T05:00:10ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682025-01-011518896Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid diseaseAdilia Mirela Pereira Lima Cid0Davi de Sá Cavalcante1Marcela Lima Gurgel2Ana Carolina Saraiva3Ana Alicia Sales Ricardo4Lúcio Mitsuo Kurita5Paulo Goberlânio de Barros Silva6Catarina Brasil d’Alva7Ana Rosa Pinto Quidute8Fabio Wildson Gurgel Costa9Division of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil; Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, USA; Corresponding author. Division of Oral Radiology, School of Dentistry, Federal University of Ceará, 1273 Monsenhor Furtado St, Fortaleza, CE, Brazil.Division of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Oral Pathology, School of Dentistry, Christus University Center, Fortaleza, Ceará, BrazilDivision of Endocrinology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Endocrinology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, BrazilDivision of Oral Radiology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, BrazilPurpose: This study aimed to assess the styloid process (TBSP) phenotype and to identify suggestive images of calcified atheromatous plaques (CAP) in panoramic radiographs of patients with primary hyperparathyroidism (PHPT) and post-surgical hypoparathyroidism (hypoPT). Additionally, it aimed to analyze the association between the bone mineral status of patients with parathyroid diseases and the radiographic findings. Material and methods: A cross-sectional case-control study was conducted with individuals diagnosed with PHPT (n = 25) and post-surgical hypoPT (n = 25). A control group (n = 50) comprised individuals without parathyroid gland disorders. Panoramic radiographs were utilized for both quantitative (length) and qualitative (mineralization patterns) evaluation of the TBSP, as well as for assessing the prevalence of CAP. Results: The frequency of TBSP exceeding 30 mm was significantly higher in the PHPT and post-surgical hypoPT groups compared to the control group. CAP occurred more frequently in the PHPT group. Cases of low bone mineral density (BMD) were associated with PHPT. In the PHPT group, low BMD was linked to an increased average TBSP length (p = 0.025) and a higher frequency of elongated TBSP (p = 0.022). Multivariate analysis revealed an inverse relationship between the T-score of the femoral neck and TBSP length in the PHPT group (p = 0.028). Conclusions: Compared to the control group, individuals with PHPT and post-surgical hypoPT showed distinct imaging findings related to TBSP and CAP. Individuals with PHPT and low BMD showed a higher frequency of elongated TBSP.http://www.sciencedirect.com/science/article/pii/S2212426824001775Primary hyperparathyroidismHypoparathyroidismPanoramic radiographyHeterotopic ossificationAtheromatous plaqueTemporal bone styloid process styloid process |
| spellingShingle | Adilia Mirela Pereira Lima Cid Davi de Sá Cavalcante Marcela Lima Gurgel Ana Carolina Saraiva Ana Alicia Sales Ricardo Lúcio Mitsuo Kurita Paulo Goberlânio de Barros Silva Catarina Brasil d’Alva Ana Rosa Pinto Quidute Fabio Wildson Gurgel Costa Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease Journal of Oral Biology and Craniofacial Research Primary hyperparathyroidism Hypoparathyroidism Panoramic radiography Heterotopic ossification Atheromatous plaque Temporal bone styloid process styloid process |
| title | Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease |
| title_full | Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease |
| title_fullStr | Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease |
| title_full_unstemmed | Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease |
| title_short | Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease |
| title_sort | styloid process phenotype and atheromatous plaque radiographic and bone density assessment in parathyroid disease |
| topic | Primary hyperparathyroidism Hypoparathyroidism Panoramic radiography Heterotopic ossification Atheromatous plaque Temporal bone styloid process styloid process |
| url | http://www.sciencedirect.com/science/article/pii/S2212426824001775 |
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