A Pathophysiologically Hypertrophic 3T3-L1 Cell Model—An Alternative to Primary Cells Isolated from DIO Mice

A Pathophysiologically Hypertrophic 3T3-L1 Cell Model—An Alternative to Primary Cells Isolated from DIO Mice

Adipocyte hypertrophy in individuals with obesity is connected to alterations in adipocyte function. These pathophysiological changes are studied using animal models and adipose tissue engineering. However, knockdown, overexpression, and stimulation studies would benefit from an easily applicable ce...

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Bibliographic Details
Main Authors: Isabell Kaczmarek, Kristiana Schüßler, Andreas Lindhorst, Martin Gericke, Doreen Thor
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
obesity
adipose tissue
adipocyte hypertrophy
cell model
Online Access:https://www.mdpi.com/2073-4409/14/11/837
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