Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada

The diminishing prevalence of Helicobacter pylori infection among most segments of the Canadian population has led to changes in the etiologies and patterns of associated upper gastrointestinal diseases, including fewer peptic ulcers and their complications. Canadian Aboriginals and recent immigrant...

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Main Authors: Nicola L Jones, Naoki Chiba, Carlo Fallone, Alan Thomson, Richard Hunt, Kevan Jacobson, Karen Goodman
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2012/174529
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author Nicola L Jones
Naoki Chiba
Carlo Fallone
Alan Thomson
Richard Hunt
Kevan Jacobson
Karen Goodman
author_facet Nicola L Jones
Naoki Chiba
Carlo Fallone
Alan Thomson
Richard Hunt
Kevan Jacobson
Karen Goodman
author_sort Nicola L Jones
collection DOAJ
description The diminishing prevalence of Helicobacter pylori infection among most segments of the Canadian population has led to changes in the etiologies and patterns of associated upper gastrointestinal diseases, including fewer peptic ulcers and their complications. Canadian Aboriginals and recent immigrants are among populations in which the prevalence of H pylori infection remains high and, therefore, the health risks imposed by H pylori remain a significant concern. Population-based strategies for H pylori eradication in groups with a low prevalence of infection are unlikely to be cost effective, but such measures are attractive in groups in which the prevalence rates of infection remain substantial. In addition to a lower prevalence of peptic ulcers and dyspepsia, the public health value of eradication may be particularly important if this leads to a reduction in the prevalence of gastric cancer in high prevalence groups. Therefore The Canadian Helicobacter Study Group held a conference that brought together experts in the field to address these issues, the results of which are reviewed in the present article. Canadians with the highest prevalence of H pylori infection are an appropriate focus for considering the health advantages of eradicating persistent infection. In Canadian communities with a high prevalence of both H pylori and gastric cancer, there remains an opportunity to test the hypothesis that H pylori infection is a treatable risk factor for malignancy.
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issn 0835-7900
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publishDate 2012-01-01
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series Canadian Journal of Gastroenterology
spelling doaj-art-a57e8198fd0c4a40abe93c59eb3753d72025-08-20T02:20:37ZengWileyCanadian Journal of Gastroenterology0835-79002012-01-012629710310.1155/2012/174529Helicobacter pylori in First Nations and Recent Immigrant Populations in CanadaNicola L Jones0Naoki Chiba1Carlo Fallone2Alan Thomson3Richard Hunt4Kevan Jacobson5Karen Goodman6Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, CanadaDivision of Gastroenterology, McMaster University, Hamilton, CanadaDivision of Gastroenterology, McGill University Health Centre, McGill University, Montreal, Quebec, CanadaDivision of General Internal Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology and Farncombe Family Digestive Health Research Center, McMaster University, Hamilton, Ontario, CanadaDivision of Gastroenterology, British Columbia’s Children’s Hospital and CFRI, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaThe diminishing prevalence of Helicobacter pylori infection among most segments of the Canadian population has led to changes in the etiologies and patterns of associated upper gastrointestinal diseases, including fewer peptic ulcers and their complications. Canadian Aboriginals and recent immigrants are among populations in which the prevalence of H pylori infection remains high and, therefore, the health risks imposed by H pylori remain a significant concern. Population-based strategies for H pylori eradication in groups with a low prevalence of infection are unlikely to be cost effective, but such measures are attractive in groups in which the prevalence rates of infection remain substantial. In addition to a lower prevalence of peptic ulcers and dyspepsia, the public health value of eradication may be particularly important if this leads to a reduction in the prevalence of gastric cancer in high prevalence groups. Therefore The Canadian Helicobacter Study Group held a conference that brought together experts in the field to address these issues, the results of which are reviewed in the present article. Canadians with the highest prevalence of H pylori infection are an appropriate focus for considering the health advantages of eradicating persistent infection. In Canadian communities with a high prevalence of both H pylori and gastric cancer, there remains an opportunity to test the hypothesis that H pylori infection is a treatable risk factor for malignancy.http://dx.doi.org/10.1155/2012/174529
spellingShingle Nicola L Jones
Naoki Chiba
Carlo Fallone
Alan Thomson
Richard Hunt
Kevan Jacobson
Karen Goodman
Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada
Canadian Journal of Gastroenterology
title Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada
title_full Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada
title_fullStr Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada
title_full_unstemmed Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada
title_short Helicobacter pylori in First Nations and Recent Immigrant Populations in Canada
title_sort helicobacter pylori in first nations and recent immigrant populations in canada
url http://dx.doi.org/10.1155/2012/174529
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