Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive
The studies were conducted at the dairy complexes of the breeding farm of the Agricultural Enterprise Kolkhoz Soznatelnyˮ, Zubtsovsky District, Tver Region, by the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals and the Medical and Diagnostic Center of the Federal...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Peoples’ Friendship University of Russia (RUDN University)
2025-12-01
|
| Series: | RUDN Journal of Agronomy and Animal Industries |
| Subjects: | |
| Online Access: | https://agrojournal.rudn.ru/agronomy/article/viewFile/20164/16471 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850106596899684352 |
|---|---|
| author | Larisa A. Gnezdilova Zhora Yu. Muradyan Yulia S. Kruglova Serafim M. Rozinsky |
| author_facet | Larisa A. Gnezdilova Zhora Yu. Muradyan Yulia S. Kruglova Serafim M. Rozinsky |
| author_sort | Larisa A. Gnezdilova |
| collection | DOAJ |
| description | The studies were conducted at the dairy complexes of the breeding farm of the Agricultural Enterprise Kolkhoz Soznatelnyˮ, Zubtsovsky District, Tver Region, by the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals and the Medical and Diagnostic Center of the Federal State Budgetary Educational Institution of Higher Education Moscow State Academy of Veterinary Medicine and Biotechnology - Moscow State Academy of Veterinary Medicine named after K.I. Skryabin. Betulin-containing feed additive was given to fiveand ten-month-old calves of the experimental groups orally at a dose of 10 mg/kg of weight with water individually once a day for 14 days. To assess the effect of betulin on the body of calves, as well as to exclude concomitant diseases, a clinical study of al[poiuylkhgfdsl experimental animals and a biochemical analysis of blood serum were conducted at the beginning and end of the experiment. The study presents the results of clinical trials of a feed additive containing the natural adaptogen betulin. The effect of betulin-containing feed additive on the biochemical parameters of the blood serum of breeding calves and highly productive dairy cattle was studied. It was established that the use of betulin-containing feed additive to calves of five and ten months of age orally at a dose of 10 mg/kg of weight with water individually 1 time per day for 14 days, normalizes the level of bilirubin in the blood serum, alanine aminotransferase and aspartate aminotransferase, alkaline phosphatase lactate dehydrogenase. By the end of the experiment, the calves of the experimental group also showed an increase in the level of total serum protein within the physiological norm. The results obtained indicate that the use of betulin-containing feed additive according to the specified scheme has an anti-inflammatory, cardioand hepatoprotective effect. An increase in the amount of total protein in calves after using the feed additive indicates a compensatory increase in the synthesis of globulin fraction proteins. |
| format | Article |
| id | doaj-art-a577a436a0be4f9993b7e9ee8d230fbc |
| institution | OA Journals |
| issn | 2312-797X 2312-7988 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Peoples’ Friendship University of Russia (RUDN University) |
| record_format | Article |
| series | RUDN Journal of Agronomy and Animal Industries |
| spelling | doaj-art-a577a436a0be4f9993b7e9ee8d230fbc2025-08-20T02:38:48ZengPeoples’ Friendship University of Russia (RUDN University)RUDN Journal of Agronomy and Animal Industries2312-797X2312-79882025-12-01201122610.22363/2312-797X-2025-20-1-12-2617115Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additiveLarisa A. Gnezdilova0https://orcid.org/0000-0003-1007-3441Zhora Yu. Muradyan1https://orcid.org/0000-0003-2516-7627Yulia S. Kruglova2https://orcid.org/0000-0003-2953-0745Serafim M. Rozinsky3https://orcid.org/0009-0001-1937-6919Moscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. SkryabinMoscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. SkryabinMoscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. SkryabinMoscow State Academy of Veterinary Medicine and Biotechnology - MBA named after K.I. SkryabinThe studies were conducted at the dairy complexes of the breeding farm of the Agricultural Enterprise Kolkhoz Soznatelnyˮ, Zubtsovsky District, Tver Region, by the Department of Disease Diagnostics, Therapy, Obstetrics and Reproduction of Animals and the Medical and Diagnostic Center of the Federal State Budgetary Educational Institution of Higher Education Moscow State Academy of Veterinary Medicine and Biotechnology - Moscow State Academy of Veterinary Medicine named after K.I. Skryabin. Betulin-containing feed additive was given to fiveand ten-month-old calves of the experimental groups orally at a dose of 10 mg/kg of weight with water individually once a day for 14 days. To assess the effect of betulin on the body of calves, as well as to exclude concomitant diseases, a clinical study of al[poiuylkhgfdsl experimental animals and a biochemical analysis of blood serum were conducted at the beginning and end of the experiment. The study presents the results of clinical trials of a feed additive containing the natural adaptogen betulin. The effect of betulin-containing feed additive on the biochemical parameters of the blood serum of breeding calves and highly productive dairy cattle was studied. It was established that the use of betulin-containing feed additive to calves of five and ten months of age orally at a dose of 10 mg/kg of weight with water individually 1 time per day for 14 days, normalizes the level of bilirubin in the blood serum, alanine aminotransferase and aspartate aminotransferase, alkaline phosphatase lactate dehydrogenase. By the end of the experiment, the calves of the experimental group also showed an increase in the level of total serum protein within the physiological norm. The results obtained indicate that the use of betulin-containing feed additive according to the specified scheme has an anti-inflammatory, cardioand hepatoprotective effect. An increase in the amount of total protein in calves after using the feed additive indicates a compensatory increase in the synthesis of globulin fraction proteins.https://agrojournal.rudn.ru/agronomy/article/viewFile/20164/16471betulinbreeding farmblood testtherapeutic doseoral administrationlive weight |
| spellingShingle | Larisa A. Gnezdilova Zhora Yu. Muradyan Yulia S. Kruglova Serafim M. Rozinsky Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive RUDN Journal of Agronomy and Animal Industries betulin breeding farm blood test therapeutic dose oral administration live weight |
| title | Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive |
| title_full | Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive |
| title_fullStr | Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive |
| title_full_unstemmed | Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive |
| title_short | Monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin-containing feed additive |
| title_sort | monitoring in biochemical parameters of blood serum of calves against the background of the use of betulin containing feed additive |
| topic | betulin breeding farm blood test therapeutic dose oral administration live weight |
| url | https://agrojournal.rudn.ru/agronomy/article/viewFile/20164/16471 |
| work_keys_str_mv | AT larisaagnezdilova monitoringinbiochemicalparametersofbloodserumofcalvesagainstthebackgroundoftheuseofbetulincontainingfeedadditive AT zhorayumuradyan monitoringinbiochemicalparametersofbloodserumofcalvesagainstthebackgroundoftheuseofbetulincontainingfeedadditive AT yuliaskruglova monitoringinbiochemicalparametersofbloodserumofcalvesagainstthebackgroundoftheuseofbetulincontainingfeedadditive AT serafimmrozinsky monitoringinbiochemicalparametersofbloodserumofcalvesagainstthebackgroundoftheuseofbetulincontainingfeedadditive |