Donor-derived cell-free DNA and miRNA monitoring for the early prediction and diagnosis of liver allograft rejection and patient outcomes

Donor-derived cell-free DNA and miRNA monitoring for the early prediction and diagnosis of liver allograft rejection and patient outcomes

IntroductionThe identification of noninvasive biomarkers for monitoring liver transplant (LT) recipients is crucial for the early detection of graft dysfunction and rejection. Donor-derived cell-free DNA (dd-cfDNA) and microRNAs (miRNAs) have been identified as promising biomarkers for assessing gra...

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Bibliographic Details
Main Authors: Judit Julian, Olga Millán, Esther Titos, Pablo Ruiz, Yiliam Fundora, Alba Díaz, Jordi Colmenero, Constantino Fondevila, Joan Anton Puig-Butillé, Mercè Brunet
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
noninvasive biomarkers
donor-derived cell-free DNA
microRNA
liver transplantation
rejection
graft dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1604200/full
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