Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis
Context: Patients with diabetic ketoacidosis (DKA) have potential complications, such as respiratory failure, cerebral edema, or acute renal injury, all of which can lead to a prolonged hospital course. Aims: This study identified risk factors for prolonged intensive care unit (ICU) stay and organ...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Pediatric Respirology and Critical Care Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/prcm.prcm_25_22 |
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| _version_ | 1849700274843680768 |
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| author | Jeffrey Eli Whang Yi-Lei Wu Jia-Yuh Chen Chew-Teng Kor Ming-Sheng Lee |
| author_facet | Jeffrey Eli Whang Yi-Lei Wu Jia-Yuh Chen Chew-Teng Kor Ming-Sheng Lee |
| author_sort | Jeffrey Eli Whang |
| collection | DOAJ |
| description | Context:
Patients with diabetic ketoacidosis (DKA) have potential complications, such as respiratory failure, cerebral edema, or acute renal injury, all of which can lead to a prolonged hospital course.
Aims:
This study identified risk factors for prolonged intensive care unit (ICU) stay and organ failure in pediatric patients with DKA.
Materials and Methods:
Patients with DKA aged <19 years admitted to the pediatric ICU of our hospital between June 2011 and May 2021 were enrolled. Demographic characteristics, initial Glasgow Coma Scale score, source of admission, biochemical values, ICU length of stay (LOS), and hospital LOS were collected. The primary outcome was to identify factors associated with prolonged (≥48 h) ICU treatment. The secondary outcomes were to identify factors associated with respiratory failure, cerebral injury, or acute renal failure.
Results:
This study enrolled 137 patients. Nonemergency room admission was associated with longer ICU LOS [adjusted odds ratio (aOR), 3.14; 95% confidence interval (CI) 1.01–9.82] compared with admission from the emergency room. Older age (aOR, 0.89; 95% CI, 0.80–0.99) and underweight (aOR, 0.33; 95% CI, 0.12–0.95) were associated with shorter ICU LOS.
Conclusions:
Recognizing the risk factors associated with prolonged ICU LOS in pediatric patients with DKA may help clinicians with the early identification of critical DKA cases. |
| format | Article |
| id | doaj-art-a5662c3823d74bf3a0ac6884f905faeb |
| institution | DOAJ |
| issn | 2543-0343 2543-0351 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pediatric Respirology and Critical Care Medicine |
| spelling | doaj-art-a5662c3823d74bf3a0ac6884f905faeb2025-08-20T03:18:19ZengWolters Kluwer Medknow PublicationsPediatric Respirology and Critical Care Medicine2543-03432543-03512023-01-0171131910.4103/prcm.prcm_25_22Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosisJeffrey Eli WhangYi-Lei WuJia-Yuh ChenChew-Teng KorMing-Sheng LeeContext: Patients with diabetic ketoacidosis (DKA) have potential complications, such as respiratory failure, cerebral edema, or acute renal injury, all of which can lead to a prolonged hospital course. Aims: This study identified risk factors for prolonged intensive care unit (ICU) stay and organ failure in pediatric patients with DKA. Materials and Methods: Patients with DKA aged <19 years admitted to the pediatric ICU of our hospital between June 2011 and May 2021 were enrolled. Demographic characteristics, initial Glasgow Coma Scale score, source of admission, biochemical values, ICU length of stay (LOS), and hospital LOS were collected. The primary outcome was to identify factors associated with prolonged (≥48 h) ICU treatment. The secondary outcomes were to identify factors associated with respiratory failure, cerebral injury, or acute renal failure. Results: This study enrolled 137 patients. Nonemergency room admission was associated with longer ICU LOS [adjusted odds ratio (aOR), 3.14; 95% confidence interval (CI) 1.01–9.82] compared with admission from the emergency room. Older age (aOR, 0.89; 95% CI, 0.80–0.99) and underweight (aOR, 0.33; 95% CI, 0.12–0.95) were associated with shorter ICU LOS. Conclusions: Recognizing the risk factors associated with prolonged ICU LOS in pediatric patients with DKA may help clinicians with the early identification of critical DKA cases.https://journals.lww.com/10.4103/prcm.prcm_25_22diabetic ketoacidosisintensive care unitpediatriclength of stay |
| spellingShingle | Jeffrey Eli Whang Yi-Lei Wu Jia-Yuh Chen Chew-Teng Kor Ming-Sheng Lee Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis Pediatric Respirology and Critical Care Medicine diabetic ketoacidosis intensive care unit pediatric length of stay |
| title | Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis |
| title_full | Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis |
| title_fullStr | Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis |
| title_full_unstemmed | Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis |
| title_short | Factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis |
| title_sort | factors associated with prolonged intensive care unit treatment and organ failure in pediatric patients with diabetic ketoacidosis |
| topic | diabetic ketoacidosis intensive care unit pediatric length of stay |
| url | https://journals.lww.com/10.4103/prcm.prcm_25_22 |
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