Comparison of light gradient boosting and logistic regression for interactomic hub genes in Porphyromonas gingivalis and Fusobacterium nucleatum-induced periodontitis with Alzheimer's disease
IntroductionPorphyromonas gingivalis and Treponema species have been found to invade the central nervous system through virulence factors, causing inflammation and influencing the host immune response. P. gingivalis interacts with astrocytes, microglia, and neurons, leading to neuroinflammation. Agg...
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| Main Authors: | Pradeep Kumar Yadalam, Shubhangini Chatterjee, Prabhu Manickam Natarajan, Carlos M. Ardila |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Oral Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/froh.2025.1463458/full |
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