Distinctive Behaviors of Druggable Proteins in Cellular Networks.
The interaction environment of a protein in a cellular network is important in defining the role that the protein plays in the system as a whole, and thus its potential suitability as a drug target. Despite the importance of the network environment, it is neglected during target selection for drug d...
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| Main Authors: | Costas Mitsopoulos, Amanda C Schierz, Paul Workman, Bissan Al-Lazikani |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-12-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1004597 |
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