Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity
Objectives. To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. Materials and Methods. A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The sensorial and quantitative tests were applied befo...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2018/7916274 |
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| author | David Gomes de Alencar Gondim Antonio Marcos Montagner Ivo Cavalcante Pita-Neto Romildo José de Siqueira Bringel Francisco Aurelio Luchesi Sandrini Eduardo Fernando Chaves Moreno Amanda Mendes de Sousa Andreza Bastos Correia |
| author_facet | David Gomes de Alencar Gondim Antonio Marcos Montagner Ivo Cavalcante Pita-Neto Romildo José de Siqueira Bringel Francisco Aurelio Luchesi Sandrini Eduardo Fernando Chaves Moreno Amanda Mendes de Sousa Andreza Bastos Correia |
| author_sort | David Gomes de Alencar Gondim |
| collection | DOAJ |
| description | Objectives. To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. Materials and Methods. A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The sensorial and quantitative tests were applied before the contact with topical anesthetic and after the application. Results. In the superficial tactile perception test, when we compared each group singly, there were statistically significant values in the decrease of superficial tactile perception when compared to the moment prior to the application of anesthetic agents. For the sensitivity to mechanical pain, no statistical significant difference was observed at evaluated times. In the needle penetration test, in an intergroup analysis, we found a decrease in the pain sensitivity to needle penetration at 5 min (p=0.053) and at 10 min (p=0.019) after the contact of the anesthetic drug with the oral mucosa. Conclusion. The application of topical anesthetic drugs reduces the discomfort associated with this procedure, mainly until the first 10 minutes. Only the needle penetration sensitivity test showed sufficient sensitivity to reveal a difference in the anesthetic effect between EMLA and benzocaine. This trial is registered with RBR-2N2GSW. |
| format | Article |
| id | doaj-art-a52e90348b3242298dcc6642f0c55bc7 |
| institution | OA Journals |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-a52e90348b3242298dcc6642f0c55bc72025-08-20T02:23:05ZengWileyInternational Journal of Dentistry1687-87281687-87362018-01-01201810.1155/2018/79162747916274Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile SensitivityDavid Gomes de Alencar Gondim0Antonio Marcos Montagner1Ivo Cavalcante Pita-Neto2Romildo José de Siqueira Bringel3Francisco Aurelio Luchesi Sandrini4Eduardo Fernando Chaves Moreno5Amanda Mendes de Sousa6Andreza Bastos Correia7São Leopoldo Mandic Institute and Research Center, Campinas, SP, BrazilSão Leopoldo Mandic Institute and Research Center, Campinas, SP, BrazilSchool of Dentistry, UNILEÃO-University Center, Juazeiro do Norte, CE, BrazilSchool of Dentistry, UNILEÃO-University Center, Juazeiro do Norte, CE, BrazilSchool of Dentistry, UNILEÃO-University Center, Juazeiro do Norte, CE, BrazilSchool of Dentistry, UNILEÃO-University Center, Juazeiro do Norte, CE, BrazilSchool of Dentistry, UNILEÃO-University Center, Juazeiro do Norte, CE, BrazilSchool of Dentistry, UNILEÃO-University Center, Juazeiro do Norte, CE, BrazilObjectives. To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. Materials and Methods. A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The sensorial and quantitative tests were applied before the contact with topical anesthetic and after the application. Results. In the superficial tactile perception test, when we compared each group singly, there were statistically significant values in the decrease of superficial tactile perception when compared to the moment prior to the application of anesthetic agents. For the sensitivity to mechanical pain, no statistical significant difference was observed at evaluated times. In the needle penetration test, in an intergroup analysis, we found a decrease in the pain sensitivity to needle penetration at 5 min (p=0.053) and at 10 min (p=0.019) after the contact of the anesthetic drug with the oral mucosa. Conclusion. The application of topical anesthetic drugs reduces the discomfort associated with this procedure, mainly until the first 10 minutes. Only the needle penetration sensitivity test showed sufficient sensitivity to reveal a difference in the anesthetic effect between EMLA and benzocaine. This trial is registered with RBR-2N2GSW.http://dx.doi.org/10.1155/2018/7916274 |
| spellingShingle | David Gomes de Alencar Gondim Antonio Marcos Montagner Ivo Cavalcante Pita-Neto Romildo José de Siqueira Bringel Francisco Aurelio Luchesi Sandrini Eduardo Fernando Chaves Moreno Amanda Mendes de Sousa Andreza Bastos Correia Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity International Journal of Dentistry |
| title | Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity |
| title_full | Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity |
| title_fullStr | Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity |
| title_full_unstemmed | Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity |
| title_short | Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity |
| title_sort | comparative analysis of the effectiveness of the topical administration of benzocaine and emla r on oral pain and tactile sensitivity |
| url | http://dx.doi.org/10.1155/2018/7916274 |
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