High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations
Background. High-grade gliomas of the brainstem are rare in adults and are particularly rare in the anterolateral medulla. We describe an illustrative case and discuss the diagnostic and treatment issues associated with a tumor in this location, including differential diagnosis, anatomical considera...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/6813089 |
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| author | Angela Spurgeon Viet Le Sanjay Konakondla Douglas C. Miller Tamera Hopkins N. Scott Litofsky |
| author_facet | Angela Spurgeon Viet Le Sanjay Konakondla Douglas C. Miller Tamera Hopkins N. Scott Litofsky |
| author_sort | Angela Spurgeon |
| collection | DOAJ |
| description | Background. High-grade gliomas of the brainstem are rare in adults and are particularly rare in the anterolateral medulla. We describe an illustrative case and discuss the diagnostic and treatment issues associated with a tumor in this location, including differential diagnosis, anatomical considerations for options for surgical management, multimodality treatment, and prognosis. Case Description. A 69-year-old woman presented with a 3-week history of progressive right lower extremity weakness. She underwent an open biopsy via a far lateral approach with partial condylectomy, which revealed a glioblastoma. Concurrent temozolomide and radiation were completed; however, she elected to stop her chemotherapy after 5.5 weeks of treatment. She succumbed to her disease 11 months after diagnosis. Conclusions. Biopsy can be performed relatively safely to provide definitive diagnosis to guide treatment, but long-term prognosis is poor. |
| format | Article |
| id | doaj-art-a521f20c6f9c4703bf7cb01d1384add9 |
| institution | OA Journals |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-a521f20c6f9c4703bf7cb01d1384add92025-08-20T02:23:05ZengWileyCase Reports in Neurological Medicine2090-66682090-66762016-01-01201610.1155/2016/68130896813089High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical ConsiderationsAngela Spurgeon0Viet Le1Sanjay Konakondla2Douglas C. Miller3Tamera Hopkins4N. Scott Litofsky5Division of Neurosurgery, University of Missouri School of Medicine, Columbia, MO 65212, USAUniversity of Missouri School of Medicine, Columbia, MO 65212, USADivision of Neurosurgery, University of Missouri School of Medicine, Columbia, MO 65212, USADepartment of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USADivision of Hematology Oncology, University of Missouri School of Medicine, Columbia, MO 65212, USADivision of Neurosurgery, University of Missouri School of Medicine, Columbia, MO 65212, USABackground. High-grade gliomas of the brainstem are rare in adults and are particularly rare in the anterolateral medulla. We describe an illustrative case and discuss the diagnostic and treatment issues associated with a tumor in this location, including differential diagnosis, anatomical considerations for options for surgical management, multimodality treatment, and prognosis. Case Description. A 69-year-old woman presented with a 3-week history of progressive right lower extremity weakness. She underwent an open biopsy via a far lateral approach with partial condylectomy, which revealed a glioblastoma. Concurrent temozolomide and radiation were completed; however, she elected to stop her chemotherapy after 5.5 weeks of treatment. She succumbed to her disease 11 months after diagnosis. Conclusions. Biopsy can be performed relatively safely to provide definitive diagnosis to guide treatment, but long-term prognosis is poor.http://dx.doi.org/10.1155/2016/6813089 |
| spellingShingle | Angela Spurgeon Viet Le Sanjay Konakondla Douglas C. Miller Tamera Hopkins N. Scott Litofsky High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations Case Reports in Neurological Medicine |
| title | High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations |
| title_full | High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations |
| title_fullStr | High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations |
| title_full_unstemmed | High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations |
| title_short | High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical Considerations |
| title_sort | high grade glioma of the ventrolateral medulla in an adult case presentation and discussion of surgical considerations |
| url | http://dx.doi.org/10.1155/2016/6813089 |
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