Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity
The plant extract of Euphorbia antiquorum was utilized to perform a green synthesis of zinc oxide nanoparticles (ZnO NPs). The phytochemical components of the nanoparticles were subsequently examined. The ZnO NPs produced through biosynthesis were analyzed using several spectroscopic methods. The pl...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Next Nanotechnology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949829525000798 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849415236744904704 |
|---|---|
| author | Surya Sivakumar Boobal Rangaswamy Lathika Shanmugam Kamalesh Marudhachalam |
| author_facet | Surya Sivakumar Boobal Rangaswamy Lathika Shanmugam Kamalesh Marudhachalam |
| author_sort | Surya Sivakumar |
| collection | DOAJ |
| description | The plant extract of Euphorbia antiquorum was utilized to perform a green synthesis of zinc oxide nanoparticles (ZnO NPs). The phytochemical components of the nanoparticles were subsequently examined. The ZnO NPs produced through biosynthesis were analyzed using several spectroscopic methods. The plant extract revealed the existence of alkaloids, tannins, flavonoids, terpenoids, gums, and mucilages, which played a role in the production of ZnO NPs by decreasing metal ions and ensuring the stability of the process. The Fourier-transform infrared spectroscopy (FTIR) revealed the unique spectra associated with ZnO NPs at a wavenumber of 455.20 cm−1. The nanoparticles were observed to have a nanoflake structure by analysis with the Field Emission Scanning Electron Microscope (FE-SEM). The average size of the crystallites was determined to be 37 nm using X-ray diffraction (XRD) patterns. The Energy-dispersive X-ray spectroscopy (EDX) spectra of ZnO NPs confirmed the nanoparticles production with very few impurities. The antibacterial efficacy of the synthesized NPs was assessed by determining the Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) against E. coli, Pseudomonas sp., Vibrio sp., and Bacillus sp. The presence of phytochemicals and the activity against microorganisms evidenced the importance of NPs to prevent infection, promote wound healing and to treat diseases. This study determines that ZnO NPs possess substantial antibacterial properties against diverse aquatic pathogens, presenting them as a viable substitute for conventional antibiotics. |
| format | Article |
| id | doaj-art-a51ae0fbba1b44608b3519676fbc8506 |
| institution | Kabale University |
| issn | 2949-8295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Next Nanotechnology |
| spelling | doaj-art-a51ae0fbba1b44608b3519676fbc85062025-08-20T03:33:35ZengElsevierNext Nanotechnology2949-82952025-01-01810021010.1016/j.nxnano.2025.100210Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activitySurya Sivakumar0Boobal Rangaswamy1Lathika Shanmugam2Kamalesh Marudhachalam3Department of Biotechnology, PSG College of Arts & Science, Coimbatore, Tamil Nadu 641014, IndiaDepartment of Biotechnology, PSG College of Arts & Science, Coimbatore, Tamil Nadu 641014, India; Corresponding author.Department of Biotechnology, PSG College of Arts & Science, Coimbatore, Tamil Nadu 641014, IndiaDepartment of Biotechnology, PSG College of Arts & Science, Coimbatore, Tamil Nadu 641014, India; Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, Tamil Nadu 641046, IndiaThe plant extract of Euphorbia antiquorum was utilized to perform a green synthesis of zinc oxide nanoparticles (ZnO NPs). The phytochemical components of the nanoparticles were subsequently examined. The ZnO NPs produced through biosynthesis were analyzed using several spectroscopic methods. The plant extract revealed the existence of alkaloids, tannins, flavonoids, terpenoids, gums, and mucilages, which played a role in the production of ZnO NPs by decreasing metal ions and ensuring the stability of the process. The Fourier-transform infrared spectroscopy (FTIR) revealed the unique spectra associated with ZnO NPs at a wavenumber of 455.20 cm−1. The nanoparticles were observed to have a nanoflake structure by analysis with the Field Emission Scanning Electron Microscope (FE-SEM). The average size of the crystallites was determined to be 37 nm using X-ray diffraction (XRD) patterns. The Energy-dispersive X-ray spectroscopy (EDX) spectra of ZnO NPs confirmed the nanoparticles production with very few impurities. The antibacterial efficacy of the synthesized NPs was assessed by determining the Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) against E. coli, Pseudomonas sp., Vibrio sp., and Bacillus sp. The presence of phytochemicals and the activity against microorganisms evidenced the importance of NPs to prevent infection, promote wound healing and to treat diseases. This study determines that ZnO NPs possess substantial antibacterial properties against diverse aquatic pathogens, presenting them as a viable substitute for conventional antibiotics.http://www.sciencedirect.com/science/article/pii/S2949829525000798NanoparticlesZnOGreen synthesisAntibacterial activity |
| spellingShingle | Surya Sivakumar Boobal Rangaswamy Lathika Shanmugam Kamalesh Marudhachalam Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity Next Nanotechnology Nanoparticles ZnO Green synthesis Antibacterial activity |
| title | Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity |
| title_full | Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity |
| title_fullStr | Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity |
| title_full_unstemmed | Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity |
| title_short | Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity |
| title_sort | phytochemical mediated zinc oxide nanoparticles from euphorbia antiquorum synthesis characterization amp antibacterial activity |
| topic | Nanoparticles ZnO Green synthesis Antibacterial activity |
| url | http://www.sciencedirect.com/science/article/pii/S2949829525000798 |
| work_keys_str_mv | AT suryasivakumar phytochemicalmediatedzincoxidenanoparticlesfromeuphorbiaantiquorumsynthesischaracterizationampantibacterialactivity AT boobalrangaswamy phytochemicalmediatedzincoxidenanoparticlesfromeuphorbiaantiquorumsynthesischaracterizationampantibacterialactivity AT lathikashanmugam phytochemicalmediatedzincoxidenanoparticlesfromeuphorbiaantiquorumsynthesischaracterizationampantibacterialactivity AT kamaleshmarudhachalam phytochemicalmediatedzincoxidenanoparticlesfromeuphorbiaantiquorumsynthesischaracterizationampantibacterialactivity |