The effect of progestagens on immunological risk factors of preterm birth
Aim. To determine the level of IgA and IgG to estradiol, progesterone, and benzo[a]pyrene in women with or without preterm labor and to assess whether the administration of progestagens affect these parameters.Materials and Methods. We measured the levels of IgA and IgG to estradiol, progesterone, a...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Kemerovo State Medical University
2019-12-01
|
| Series: | Фундаментальная и клиническая медицина |
| Subjects: | |
| Online Access: | https://fcm.kemsmu.ru/jour/article/view/186 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850064825954074624 |
|---|---|
| author | N. N. Elizarova N. V. Artymuk E. G. Polenok |
| author_facet | N. N. Elizarova N. V. Artymuk E. G. Polenok |
| author_sort | N. N. Elizarova |
| collection | DOAJ |
| description | Aim. To determine the level of IgA and IgG to estradiol, progesterone, and benzo[a]pyrene in women with or without preterm labor and to assess whether the administration of progestagens affect these parameters.Materials and Methods. We measured the levels of IgA and IgG to estradiol, progesterone, and benzo[a]pyrene in serum of 199 pregnant women (68 with PL and 81 with normal delivery) with the following analysis of associations between progestagen administration and these parameters.Results. The level of IgA to estradiol in patients with preterm labor was significantly higher than in women with normal delivery, and the administration of progestagens did not reduce their level in women with preterm birth.Conclusions. Measurement of the antibodies to estradiol may help in predicting pregnancy complications such as preterm birth. |
| format | Article |
| id | doaj-art-a50c97adc2cf49eebf871fffd77976ff |
| institution | DOAJ |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2019-12-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-a50c97adc2cf49eebf871fffd77976ff2025-08-20T02:49:10ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412019-12-0144263110.23946/2500-0764-2019-4-4-26-31172The effect of progestagens on immunological risk factors of preterm birthN. N. Elizarova0N. V. Artymuk1E. G. Polenok2Belyaev Kemerovo Regional HospitalKemerovo State Medical UniversityInstitute of Human Ecology Siberian Branch of Russian Academy of SciencesAim. To determine the level of IgA and IgG to estradiol, progesterone, and benzo[a]pyrene in women with or without preterm labor and to assess whether the administration of progestagens affect these parameters.Materials and Methods. We measured the levels of IgA and IgG to estradiol, progesterone, and benzo[a]pyrene in serum of 199 pregnant women (68 with PL and 81 with normal delivery) with the following analysis of associations between progestagen administration and these parameters.Results. The level of IgA to estradiol in patients with preterm labor was significantly higher than in women with normal delivery, and the administration of progestagens did not reduce their level in women with preterm birth.Conclusions. Measurement of the antibodies to estradiol may help in predicting pregnancy complications such as preterm birth.https://fcm.kemsmu.ru/jour/article/view/186premature rupture of membranespreterm birthprematuritybenzo[a]pyreneestradiolprogesterone |
| spellingShingle | N. N. Elizarova N. V. Artymuk E. G. Polenok The effect of progestagens on immunological risk factors of preterm birth Фундаментальная и клиническая медицина premature rupture of membranes preterm birth prematurity benzo[a]pyrene estradiol progesterone |
| title | The effect of progestagens on immunological risk factors of preterm birth |
| title_full | The effect of progestagens on immunological risk factors of preterm birth |
| title_fullStr | The effect of progestagens on immunological risk factors of preterm birth |
| title_full_unstemmed | The effect of progestagens on immunological risk factors of preterm birth |
| title_short | The effect of progestagens on immunological risk factors of preterm birth |
| title_sort | effect of progestagens on immunological risk factors of preterm birth |
| topic | premature rupture of membranes preterm birth prematurity benzo[a]pyrene estradiol progesterone |
| url | https://fcm.kemsmu.ru/jour/article/view/186 |
| work_keys_str_mv | AT nnelizarova theeffectofprogestagensonimmunologicalriskfactorsofpretermbirth AT nvartymuk theeffectofprogestagensonimmunologicalriskfactorsofpretermbirth AT egpolenok theeffectofprogestagensonimmunologicalriskfactorsofpretermbirth AT nnelizarova effectofprogestagensonimmunologicalriskfactorsofpretermbirth AT nvartymuk effectofprogestagensonimmunologicalriskfactorsofpretermbirth AT egpolenok effectofprogestagensonimmunologicalriskfactorsofpretermbirth |