Systematic Characterization of Splicing Dysregulation in Pan Solid Tumor Transcriptome
Abstract Splicing dysregulation arising from spliceosomal mutations contributes to disease progression and treatment resistance, mostly in hematologic malignancy. Whereas spliceosomal mutations are less common in solid tumors, splicing disorders are pervasive and proven to promote tumorigenesis. How...
Saved in:
Main Authors: | Jingru Sui, Dan Guo, Xiao Wen, Lei Zhou, Yue Huang, Haoyu Yu, Jinyu Chen, Zhaoqi Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2025-01-01
|
Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202405626 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting RNA splicing modulation: new perspectives for anticancer strategy?
by: Xuemei Lv, et al.
Published: (2025-01-01) -
Alternative Splicing: Emerging Roles in Anti-Aging Strategies
by: Lingyue Gao, et al.
Published: (2025-01-01) -
Identification of neoantigens derived from alternative splicing and RNA modification
by: Jiyeon Park, et al.
Published: (2019-08-01) -
The role of ESRP1 in solid tumor development through the regulation of CD44 splicing and EMT processes
by: Lili Wang, et al.
Published: (2025-02-01) -
Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes
by: K. V. Ustyantsev, et al.
Published: (2021-03-01)