Cancer-derived exosomal circTMEM56 enhances the efficacy of HCC radiotherapy through the miR-136-5p/STING axis

Cancer-derived exosomal circTMEM56 enhances the efficacy of HCC radiotherapy through the miR-136-5p/STING axis

Objective: Although the role of circular RNAs (circRNAs) in tumor progression and immune regulation is well-known, the specific circRNA molecules that mediate immune responses after radiotherapy (RT) and the underlying mechanisms have not been identified. Methods: Cytometry with time-of-flight (CyTO...

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Bibliographic Details
Main Authors: Li Yuan, Yue Wang, Junjie Cheng, Shilin Lin, Aying Ma, Kunchao Li, Yiming Zheng, Zhaochong Zeng, Aiwu Ke, Chao Gao, Shisuo Du
Format: Article
Language:English
Published: China Anti-Cancer Association 2025-04-01
Series:Cancer Biology & Medicine
Subjects:
circtmem56
hepatocellular carcinoma
cgas-sting
radiotherapy
dendritic cell
Online Access:https://www.cancerbiomed.org/content/22/4/396
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