With great power, comes great responsibility: the importance of broadly measuring Fc-mediated effector function early in the antibody development process

The field of antibody therapeutics is rapidly growing, with over 210 antibodies currently approved or in regulatory review and ~ 1,250 antibodies in clinical development. Antibodies are highly versatile molecules that, with strategic design of their antigen-binding domain (Fab) and the domain respon...

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Bibliographic Details
Main Authors: Silvia Crescioli, Shashi Jatiani, Lenny Moise
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
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Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2453515
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