Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis

Abstract Background Self-management is significant for the quality of life, physical and mental health, and prognosis of patients with epilepsy. There is evidence that various factors significantly affect the level of self-management in people with epilepsy, however, the reported factors affecting s...

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Main Authors: Wenhao Tian, Xiaoxiao Yin, Wanya Pan, Chang Liu, Yuan Zhao, Leiwen Tang, Xiuqin Feng
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Nursing
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Online Access:https://doi.org/10.1186/s12912-025-03063-3
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author Wenhao Tian
Xiaoxiao Yin
Wanya Pan
Chang Liu
Yuan Zhao
Leiwen Tang
Xiuqin Feng
author_facet Wenhao Tian
Xiaoxiao Yin
Wanya Pan
Chang Liu
Yuan Zhao
Leiwen Tang
Xiuqin Feng
author_sort Wenhao Tian
collection DOAJ
description Abstract Background Self-management is significant for the quality of life, physical and mental health, and prognosis of patients with epilepsy. There is evidence that various factors significantly affect the level of self-management in people with epilepsy, however, the reported factors affecting self-management vary greatly. Therefore, it is particularly important to further unify and clarify the factors affecting self-management in people with epilepsy. Aims This study aimed to identify the influencing factors of epilepsy self-management, and provide help for researchers to develop more accurate intervention strategies and interventions. Design A systematic review and meta-analysis. Data sources From online databases, including PubMed, Web of Science, CINAHL, Embase, Cochrane Library, China National Knowledge Infrastructure, China Science and Technology Journal Database and Wan Fang Data. Review methods Two independent systematic searches of English and Chinese databases were conducted by two graduate students with evidence-based training. The searches combined MeSH terms and free terms and covered the period from the establishment of the databases to October 31, 2024. References were managed using EndNote 20. Then, two reviewers independently screened literature, assessed study eligibility using the Agency for Healthcare Research and Quality (AHRQ) and extracted data. After conducting a quality assessment of the included literature, meta-analysis was performed by using the obtained data. The degree of heterogeneity was also indicated by using I2 statistic. Results In 10 cross-sectional studies were selected from 2720 studies, Education, Gender, Income level, Employment, Marital status, Age, Duration of disease, Self-efficacy may be key factors affecting self-management in patients with epilepsy. Meanwhile, the meta-analysis result of Education(0.53, 95% confidence interval (CI):0.25 ~ 0.58), Gender(0.35, 95%CI:0.18 ~ 0.51), Income level(0.41, 95%CI:0.18 ~ 0.51), Employment(-0.49, 95%CI: -0.63 ~ 0.36), Marital status(-0.28, 95%CI: -0.43 ~ 0.13), Age(0.12, 95%CI:0.01 ~ 0.23), Duration of disease(0.47, 95%CI:0.11 ~ 0.83), Self-efficacy(0.28, 95%CI:0.21 ~ 0.35) were statistically significant (P<0.05) and result of Frequency of seizure(0.3, 95%CI:-0.63 ~ 1.22) was not significant(P>0.05). Conclusion The status of self-management in patients with epilepsy in some regions is still not optimistic. In this review, self-management in patients with epilepsy is affected by many factors, including education, age, self-efficacy, employment, marital status, duration of disease, gender, income level. These factors may provide more targeted interventions and education to improve the self-management and quality of life of epilepsy patients. Registration www.crd.york.ac.uk CRD42024619449, registered 10/12/2024.
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spelling doaj-art-a4e85baefae449fbbb1d78960e255cc32025-08-20T02:30:22ZengBMCBMC Nursing1472-69552025-04-012411910.1186/s12912-025-03063-3Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysisWenhao Tian0Xiaoxiao Yin1Wanya Pan2Chang Liu3Yuan Zhao4Leiwen Tang5Xiuqin Feng6Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU)Abstract Background Self-management is significant for the quality of life, physical and mental health, and prognosis of patients with epilepsy. There is evidence that various factors significantly affect the level of self-management in people with epilepsy, however, the reported factors affecting self-management vary greatly. Therefore, it is particularly important to further unify and clarify the factors affecting self-management in people with epilepsy. Aims This study aimed to identify the influencing factors of epilepsy self-management, and provide help for researchers to develop more accurate intervention strategies and interventions. Design A systematic review and meta-analysis. Data sources From online databases, including PubMed, Web of Science, CINAHL, Embase, Cochrane Library, China National Knowledge Infrastructure, China Science and Technology Journal Database and Wan Fang Data. Review methods Two independent systematic searches of English and Chinese databases were conducted by two graduate students with evidence-based training. The searches combined MeSH terms and free terms and covered the period from the establishment of the databases to October 31, 2024. References were managed using EndNote 20. Then, two reviewers independently screened literature, assessed study eligibility using the Agency for Healthcare Research and Quality (AHRQ) and extracted data. After conducting a quality assessment of the included literature, meta-analysis was performed by using the obtained data. The degree of heterogeneity was also indicated by using I2 statistic. Results In 10 cross-sectional studies were selected from 2720 studies, Education, Gender, Income level, Employment, Marital status, Age, Duration of disease, Self-efficacy may be key factors affecting self-management in patients with epilepsy. Meanwhile, the meta-analysis result of Education(0.53, 95% confidence interval (CI):0.25 ~ 0.58), Gender(0.35, 95%CI:0.18 ~ 0.51), Income level(0.41, 95%CI:0.18 ~ 0.51), Employment(-0.49, 95%CI: -0.63 ~ 0.36), Marital status(-0.28, 95%CI: -0.43 ~ 0.13), Age(0.12, 95%CI:0.01 ~ 0.23), Duration of disease(0.47, 95%CI:0.11 ~ 0.83), Self-efficacy(0.28, 95%CI:0.21 ~ 0.35) were statistically significant (P<0.05) and result of Frequency of seizure(0.3, 95%CI:-0.63 ~ 1.22) was not significant(P>0.05). Conclusion The status of self-management in patients with epilepsy in some regions is still not optimistic. In this review, self-management in patients with epilepsy is affected by many factors, including education, age, self-efficacy, employment, marital status, duration of disease, gender, income level. These factors may provide more targeted interventions and education to improve the self-management and quality of life of epilepsy patients. Registration www.crd.york.ac.uk CRD42024619449, registered 10/12/2024.https://doi.org/10.1186/s12912-025-03063-3Self-managementEpilepsyInfluencing factorsSystematic reviewMeta-analysis
spellingShingle Wenhao Tian
Xiaoxiao Yin
Wanya Pan
Chang Liu
Yuan Zhao
Leiwen Tang
Xiuqin Feng
Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis
BMC Nursing
Self-management
Epilepsy
Influencing factors
Systematic review
Meta-analysis
title Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis
title_full Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis
title_fullStr Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis
title_full_unstemmed Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis
title_short Factors influencing self-management in patients with epilepsy: a systematic review and meta-analysis
title_sort factors influencing self management in patients with epilepsy a systematic review and meta analysis
topic Self-management
Epilepsy
Influencing factors
Systematic review
Meta-analysis
url https://doi.org/10.1186/s12912-025-03063-3
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