Striatal Toe: Too Harmless to Treat?

A striatal toe is a misalignment of the hallux in dorsal flexion that frequently presents as a symptom of Parkinson’s disease and also atypical Parkinson syndromes. It can negatively impact patients during activities such as walking, putting on socks and shoes, and particularly while wearing shoes....

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Main Authors: Wolfgang H. Jost, Emir Berberovic
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/17/4/168
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author Wolfgang H. Jost
Emir Berberovic
author_facet Wolfgang H. Jost
Emir Berberovic
author_sort Wolfgang H. Jost
collection DOAJ
description A striatal toe is a misalignment of the hallux in dorsal flexion that frequently presents as a symptom of Parkinson’s disease and also atypical Parkinson syndromes. It can negatively impact patients during activities such as walking, putting on socks and shoes, and particularly while wearing shoes. It causes pain and thus induces a loss of quality of life. But, to date, we have few data on the topics of the prevalence, genesis, and therapy of striatal toe. Publications available on botulinum neurotoxin (BoNT) have demonstrated a positive effect in the treatment of striatal toe, although the current study data are also rather limited in this area. Commensurate approval studies have not yet been performed. We will introduce our contemporary data on therapy for striatal toe with BoNT and we will also discuss possible questions open for further study.
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series Toxins
spelling doaj-art-a4dabd2a032e4a57abe097eee7c3e24b2025-08-20T02:18:10ZengMDPI AGToxins2072-66512025-04-0117416810.3390/toxins17040168Striatal Toe: Too Harmless to Treat?Wolfgang H. Jost0Emir Berberovic1Parkinson-Klinik Ortenau, 77709 Wolfach, GermanyParkinson-Klinik Ortenau, 77709 Wolfach, GermanyA striatal toe is a misalignment of the hallux in dorsal flexion that frequently presents as a symptom of Parkinson’s disease and also atypical Parkinson syndromes. It can negatively impact patients during activities such as walking, putting on socks and shoes, and particularly while wearing shoes. It causes pain and thus induces a loss of quality of life. But, to date, we have few data on the topics of the prevalence, genesis, and therapy of striatal toe. Publications available on botulinum neurotoxin (BoNT) have demonstrated a positive effect in the treatment of striatal toe, although the current study data are also rather limited in this area. Commensurate approval studies have not yet been performed. We will introduce our contemporary data on therapy for striatal toe with BoNT and we will also discuss possible questions open for further study.https://www.mdpi.com/2072-6651/17/4/168striatal toebotulinum neurotoxinParkinson’s disease
spellingShingle Wolfgang H. Jost
Emir Berberovic
Striatal Toe: Too Harmless to Treat?
Toxins
striatal toe
botulinum neurotoxin
Parkinson’s disease
title Striatal Toe: Too Harmless to Treat?
title_full Striatal Toe: Too Harmless to Treat?
title_fullStr Striatal Toe: Too Harmless to Treat?
title_full_unstemmed Striatal Toe: Too Harmless to Treat?
title_short Striatal Toe: Too Harmless to Treat?
title_sort striatal toe too harmless to treat
topic striatal toe
botulinum neurotoxin
Parkinson’s disease
url https://www.mdpi.com/2072-6651/17/4/168
work_keys_str_mv AT wolfganghjost striataltoetooharmlesstotreat
AT emirberberovic striataltoetooharmlesstotreat