Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series

Apical hypertrophic cardiomyopathy (HCM) or Yamaguchi syndrome is a relatively rare subtype of HCM characterized by a left ventricular apex localization of the hypertrophy. In this case, chest pain can be erroneously interpreted as a manifestation of coronary artery disease. This article presents tw...

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Main Authors: D. Yu. Goncharova, G. R. Bikbaeva, A. A. Tukhbatova, I. S. Mullova, D. V. Duplyakov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2022-12-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/5262
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author D. Yu. Goncharova
G. R. Bikbaeva
A. A. Tukhbatova
I. S. Mullova
D. V. Duplyakov
author_facet D. Yu. Goncharova
G. R. Bikbaeva
A. A. Tukhbatova
I. S. Mullova
D. V. Duplyakov
author_sort D. Yu. Goncharova
collection DOAJ
description Apical hypertrophic cardiomyopathy (HCM) or Yamaguchi syndrome is a relatively rare subtype of HCM characterized by a left ventricular apex localization of the hypertrophy. In this case, chest pain can be erroneously interpreted as a manifestation of coronary artery disease. This article presents two cases of apical HCM in patients admitted with a diagnosis of acute coronary syndrome. Electrocardiogram revealed repolarization disorder and giant T wave inversion (up to 10 mm) in the precordial leads. Transthoracic echocardiography revealed local symmetric hypertrophy of the left ventricular apex, which made it possible to diagnose apical HCM. The coronary arteries in both patients were intact. The presented cases demonstrate a variant of apical HCM with chest pain as the leading clinical syndrome, which can often be the cause of overdiagnosis of acute coronary syndrome.
format Article
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institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2022-12-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-a4d2f94028084bfb89e21e3a18b741a42025-08-20T03:57:22Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-12-01274S10.15829/1560-4071-2022-52623728Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case seriesD. Yu. Goncharova0G. R. Bikbaeva1A. A. Tukhbatova2I. S. Mullova3D. V. Duplyakov4Samara State Medical UniversityV. P. Polyakov Samara Regional Clinical Cardiology DispensarySamara State Medical UniversitySamara State Medical University; V. P. Polyakov Samara Regional Clinical Cardiology DispensarySamara State Medical University; V. P. Polyakov Samara Regional Clinical Cardiology DispensaryApical hypertrophic cardiomyopathy (HCM) or Yamaguchi syndrome is a relatively rare subtype of HCM characterized by a left ventricular apex localization of the hypertrophy. In this case, chest pain can be erroneously interpreted as a manifestation of coronary artery disease. This article presents two cases of apical HCM in patients admitted with a diagnosis of acute coronary syndrome. Electrocardiogram revealed repolarization disorder and giant T wave inversion (up to 10 mm) in the precordial leads. Transthoracic echocardiography revealed local symmetric hypertrophy of the left ventricular apex, which made it possible to diagnose apical HCM. The coronary arteries in both patients were intact. The presented cases demonstrate a variant of apical HCM with chest pain as the leading clinical syndrome, which can often be the cause of overdiagnosis of acute coronary syndrome.https://russjcardiol.elpub.ru/jour/article/view/5262yamaguchi syndromeapical hypertrophic cardiomyopathyacute coronary syndromediagnostic imaging
spellingShingle D. Yu. Goncharova
G. R. Bikbaeva
A. A. Tukhbatova
I. S. Mullova
D. V. Duplyakov
Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series
Российский кардиологический журнал
yamaguchi syndrome
apical hypertrophic cardiomyopathy
acute coronary syndrome
diagnostic imaging
title Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series
title_full Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series
title_fullStr Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series
title_full_unstemmed Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series
title_short Apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome: a case series
title_sort apical hypertrophic cardiomyopathy as a mask of acute coronary syndrome a case series
topic yamaguchi syndrome
apical hypertrophic cardiomyopathy
acute coronary syndrome
diagnostic imaging
url https://russjcardiol.elpub.ru/jour/article/view/5262
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AT grbikbaeva apicalhypertrophiccardiomyopathyasamaskofacutecoronarysyndromeacaseseries
AT aatukhbatova apicalhypertrophiccardiomyopathyasamaskofacutecoronarysyndromeacaseseries
AT ismullova apicalhypertrophiccardiomyopathyasamaskofacutecoronarysyndromeacaseseries
AT dvduplyakov apicalhypertrophiccardiomyopathyasamaskofacutecoronarysyndromeacaseseries