Deletion of Mex3c gene leads to autistic-like behavior in mice by inhibiting AMPK signal pathway

Deletion of Mex3c gene leads to autistic-like behavior in mice by inhibiting AMPK signal pathway

IntroductionAutism Spectrum Disorder (ASD) is a hereditary neurodevelopmental condition influenced by genetic alterations, particularly in genes regulating neural development and synaptic plasticity. Emerging evidence suggests that the Mex3c gene plays a role in energy metabolism and neuronal develo...

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Bibliographic Details
Main Authors: Hui Cai, Chengping Zhang, Haonan Zhang, Yong Du, Kai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
autism spectrum disorder
mitochondrial function
Mex3c
synaptic plasticity
social behavior
neurodevelopment
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2025.1551440/full
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