Ghrelin–LEAP2 interactions along the stomach–liver axis

Ghrelin produced in the stomach promotes food intake and GH secretion, and acts as an anabolic peptide during starvation. Ghrelin binds to the growth hormone secretagogue receptor, a G protein-coupled receptor (GPCR), whose high-resolution complex structures have been determined in the apo state and...

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Bibliographic Details
Main Authors: Katsuya Sakai, Yuki Nakazato, Yuki Shiimura, Weidong Zhang, Masamitsu Nakazato
Format: Article
Language:English
Published: The Japan Endocrine Society 2025-04-01
Series:Endocrine Journal
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Online Access:https://www.jstage.jst.go.jp/article/endocrj/72/4/72_EJ24-0543/_html/-char/en
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