Revealing age-related changes in the intraocular microenvironment and senescence modulators using aqueous humor proteomics and machine learning

Revealing age-related changes in the intraocular microenvironment and senescence modulators using aqueous humor proteomics and machine learning

BackgroundIn conjunction with age, aqueous humor (AH) proteomics can affect the occurrence and development of age-related eye diseases, which are poorly understood.ObjectiveWe characterized the proteomic changes in AH throughout the aging process to better understand the aging mechanisms of the intr...

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Main Authors: Xiaosheng Huang, Tiansheng Chou, Xinhua Liu, Kun Zeng, Liangnan Sun, Zonghui Yan, Shaoyi Mei, Wenqun Xi, Zongyi Zhan, Yi Liu, Songguo Dong, Siqi Liu, Jun Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
proteomes
aqueous humor
aging protein
senescence modulator
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1583330/full
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