Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Oncogene‐induced replication stress (RS) is a vulnerability of cancer cells that forces reliance on the intra‐S‐phase checkpoint to ensure faithful genome duplication. Inhibitors of the intra‐S‐phase checkpoint kinases ATR and CHK1 have been developed, but resistance to these drugs remains problemat...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-06-01
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| Series: | Molecular Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/1878-0261.13819 |
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