基于cGAS-STING通路和突触融合蛋白17介导的自噬在脑缺血再灌注损伤中的作用研究进展 Research Progress on the Role of cGAS-STING Pathway and Syntaxin 17 Mediated Autophagy in Cerebral Ischemia-Reperfusion Injury
急性缺血性卒中后，脑缺血再灌注损伤（cerebral ischemia-reperfusion injury，CIRI）可进一步损伤患者的神经功能，影响其预后。自噬在CIRI的病理过程中是一把“双刃剑”，其不同的激活程度以及在CIRI的不同时期，可对脑组织产生保护或损伤的相反作用。环鸟苷酸-腺苷酸合酶（cyclic guanosine monophosphate-adenosine monophosphate synthase，cGAS）-干扰素基因刺激因子（stimulator of interferon gene，STING）通路是先天免疫中重要的效应通路，突触融合蛋白17（syntaxi...
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Chinese Journal of Stroke
2025-04-01
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| Series: | Zhongguo cuzhong zazhi |
| Subjects: | |
| Online Access: | https://www.chinastroke.org.cn/CN/10.3969/j.issn.1673-5765.2025.04.012 |
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