Anti-angiogenic effects of cationic zinc (II) phthalocyanine derivatives through photodynamic therapy

Anti-angiogenic effects of cationic zinc (II) phthalocyanine derivatives through photodynamic therapy

Abstract In this study, the in vitro photodynamic therapy (PDT) activity of two zinc phthalocyanines (ZnPc1 and ZnPc2) was systematically examined in human umbilical vein endothelial cells, focusing on PDT-induced cytotoxicity, reactive oxygen species (ROS) generation, and inhibition of angiogenic p...

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Bibliographic Details
Main Authors: Seyma Isik, Mukaddes Ozcesmeci, Ayfer Kalkan Burat, Esin Hamuryudan, Ozge Can, Muge Serhatli
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Angiogenesis
Photodynamic therapy
Phthalocyanine
Migration
Invasion
Online Access:https://doi.org/10.1038/s41598-024-84674-9
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