Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease

ABSTRACT Objective Patients with Parkinson’s disease (PD) may present with unusual motor and non-motor symptoms and signs in the early stage of the disease. Methods Cases were collected over a five-year period at two tertiary movement disorders clinics. All had a diagnosis of PD with unusual pre...

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Main Authors: Hélio A. G. Teive, Délcio C. Bertucci Filho, Renato P. Munhoz
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000781&lng=en&tlng=en
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author Hélio A. G. Teive
Délcio C. Bertucci Filho
Renato P. Munhoz
author_facet Hélio A. G. Teive
Délcio C. Bertucci Filho
Renato P. Munhoz
author_sort Hélio A. G. Teive
collection DOAJ
description ABSTRACT Objective Patients with Parkinson’s disease (PD) may present with unusual motor and non-motor symptoms and signs in the early stage of the disease. Methods Cases were collected over a five-year period at two tertiary movement disorders clinics. All had a diagnosis of PD with unusual presentations defined retrospectively as the presence of complaints not objectively related to any of the classic cardinal signs of parkinsonism or the typical early non-motor features of PD. Results A total of 15 early PD patients fulfilled the proposed criteria, presenting with symptoms such as atypical tremors, shoulder pain, signs related to the rigid akinetic syndrome, as well as cases of asthenia, rhinorrhea, parosmia, dysgeusia, nocturnal sialorrhea, and color discrimination disorders. Conclusions Unusual motor and non-motor symptoms and signs in the early stage of PD can be difficult to interpret. Specialists should be aware of these conditions as clues to a potential diagnosis.
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spelling doaj-art-a4a4712749e04970954ba8b7cb0ef4e32025-08-20T03:38:14ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-4227741078178410.1590/0004-282X20160126S0004-282X2016001000781Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s diseaseHélio A. G. TeiveDélcio C. Bertucci FilhoRenato P. MunhozABSTRACT Objective Patients with Parkinson’s disease (PD) may present with unusual motor and non-motor symptoms and signs in the early stage of the disease. Methods Cases were collected over a five-year period at two tertiary movement disorders clinics. All had a diagnosis of PD with unusual presentations defined retrospectively as the presence of complaints not objectively related to any of the classic cardinal signs of parkinsonism or the typical early non-motor features of PD. Results A total of 15 early PD patients fulfilled the proposed criteria, presenting with symptoms such as atypical tremors, shoulder pain, signs related to the rigid akinetic syndrome, as well as cases of asthenia, rhinorrhea, parosmia, dysgeusia, nocturnal sialorrhea, and color discrimination disorders. Conclusions Unusual motor and non-motor symptoms and signs in the early stage of PD can be difficult to interpret. Specialists should be aware of these conditions as clues to a potential diagnosis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000781&lng=en&tlng=enParkinson diseasesigns and symptoms
spellingShingle Hélio A. G. Teive
Délcio C. Bertucci Filho
Renato P. Munhoz
Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease
Arquivos de Neuro-Psiquiatria
Parkinson disease
signs and symptoms
title Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease
title_full Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease
title_fullStr Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease
title_full_unstemmed Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease
title_short Unusual motor and non-motor symptoms and signs in the early stage of Parkinson’s disease
title_sort unusual motor and non motor symptoms and signs in the early stage of parkinson s disease
topic Parkinson disease
signs and symptoms
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001000781&lng=en&tlng=en
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AT renatopmunhoz unusualmotorandnonmotorsymptomsandsignsintheearlystageofparkinsonsdisease